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Immunogenicity, safety, and efficacy of sequential immunizations with an SIV-based IDLV expressing CH505 Envs

A preventative HIV-1 vaccine is an essential intervention needed to halt the HIV-1 pandemic. Neutralizing antibodies protect against HIV-1 infection in animal models, and thus an approach toward a protective HIV-1 vaccine is to induce broadly cross-reactive neutralizing antibodies (bnAbs). One strat...

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Detalles Bibliográficos
Autores principales:	Blasi, Maria, Negri, Donatella, Saunders, Kevin O., Baker, Erich J., Stadtler, Hannah, LaBranche, Celia, Mildenberg, Benjamin, Morton, Georgeanna, Ciarla, Andrew, Shen, Xiaoying, Wang, Yunfei, Rountree, Wes, Balakumaran, Bala, Santra, Sampa, Haynes, Barton F., Moody, Anthony M., Cara, Andrea, Klotman, Mary E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674457/ https://www.ncbi.nlm.nih.gov/pubmed/33298954 http://dx.doi.org/10.1038/s41541-020-00252-w

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