Development of Neuroregenerative Gene Therapy to Reverse Glial Scar Tissue Back to Neuron-Enriched Tissue

Injuries in the central nervous system (CNS) often causes neuronal loss and glial scar formation. We have recently demonstrated NeuroD1-mediated direct conversion of reactive glial cells into functional neurons in adult mouse brains. Here, we further investigate whether such direct glia-to-neuron co...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Lei, Zhuofan, Guo, Ziyuan, Pei, Zifei, Chen, Yuchen, Zhang, Fengyu, Cai, Alice, Mok, Gabriel, Lee, Grace, Swaminathan, Vishal, Wang, Fan, Bai, Yuting, Chen, Gong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cellular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674596/
https://www.ncbi.nlm.nih.gov/pubmed/33250718
http://dx.doi.org/10.3389/fncel.2020.594170

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