Cargando…

Novel Insights Into Epigenetic Reprogramming and Destabilization of Pericentromeric Heterochromatin in Cancer

Pericentromeric heterochromatin is maintained in a condensed structure by repressive epigenetic control mechanisms and perturbation of these may cause diseases. The chromosome 1q12 region harbors the largest pericentromeric heterochromatin domain in the genome and is among the most common breakpoint...

Descripción completa

Detalles Bibliográficos
Autor principal:	Gjerstorff, Morten Frier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674669/ https://www.ncbi.nlm.nih.gov/pubmed/33251148 http://dx.doi.org/10.3389/fonc.2020.594163

Ejemplares similares

Interaction between Polycomb and SSX Proteins in Pericentromeric Heterochromatin Function and Its Implication in Cancer
por: Johansen, Simone, et al.
Publicado: (2020)

Remodeling and destabilization of chromosome 1 pericentromeric heterochromatin by SSX proteins
por: Traynor, Sofie, et al.
Publicado: (2019)

Establishment of pericentromeric heterochromatin in development
por: Santenard, Angele, et al.
Publicado: (2013)

Heterochromatin establishment at pericentromeres depends on nuclear position
por: Jachowicz, Joanna W., et al.
Publicado: (2013)

Epigenetic targeting of myeloid-derived suppressor cells: time to move into infectious diseases?
por: Gjerstorff, Morten Frier
Publicado: (2023)

Structure and Function of Centromeric and Pericentromeric Heterochromatin in Arabidopsis thaliana
por: Simon, Lauriane, et al.
Publicado: (2015)

Tet1 regulates epigenetic remodeling of the pericentromeric heterochromatin and chromocenter organization in DNA hypomethylated cells
por: Hagihara, Yota, et al.
Publicado: (2021)

Evolutionary Dynamics of the Pericentromeric Heterochromatin in Drosophila virilis and Related Species
por: Rezvykh, Alexander P., et al.
Publicado: (2021)

The Chromatin of Candida albicans Pericentromeres Bears Features of Both Euchromatin and Heterochromatin
por: Freire-Benéitez, Verónica, et al.
Publicado: (2016)

The Human Polycomb Group Complex Associates with Pericentromeric Heterochromatin to Form a Novel Nuclear Domain
por: Saurin, Andrew J., et al.
Publicado: (1998)

Crosstalk between interferon and interleukin-1 antiviral signaling in cancer cells: implications for immune evasion and therapeutic resistance
por: Gjerstorff, Morten Frier
Publicado: (2023)

Active retrotransposons help maintain pericentromeric heterochromatin required for faithful cell division
por: Hao, Yajing, et al.
Publicado: (2020)

Loss of Tau protein affects the structure, transcription and repair of neuronal pericentromeric heterochromatin
por: Mansuroglu, Zeyni, et al.
Publicado: (2016)

Selective pericentromeric heterochromatin dismantling caused by TP53 activation during senescence
por: Mendez-Bermudez, Aaron, et al.
Publicado: (2022)

Role for rodent Smc6 in pericentromeric heterochromatin domains during spermatogonial differentiation and meiosis
por: Verver, D E, et al.
Publicado: (2013)

The pluripotency factor Nanog regulates pericentromeric heterochromatin organization in mouse embryonic stem cells
por: Novo, Clara Lopes, et al.
Publicado: (2016)

The Telomeric Protein TRF2 Regulates Replication Origin Activity within Pericentromeric Heterochromatin
por: Bauwens, Serge, et al.
Publicado: (2021)

HP1 proteins regulate nucleolar structure and function by secluding pericentromeric constitutive heterochromatin
por: Ballmer, Daniel, et al.
Publicado: (2022)

The chromatin remodeler RSC prevents ectopic CENP-A propagation into pericentromeric heterochromatin at the chromatin boundary
por: Tsunemine, Satoru, et al.
Publicado: (2022)

Ectopic Expression of Testis Germ Cell Proteins in Cancer and Its Potential Role in Genomic Instability
por: Nielsen, Aaraby Yoheswaran, et al.
Publicado: (2016)

Heterochromatin Protein 1 (HP1) Proteins Do Not Drive Pericentromeric Cohesin Enrichment in Human Cells
por: Serrano, Ángel, et al.
Publicado: (2009)

The pericentromeric heterochromatin of homologous chromosomes remains associated after centromere pairing dissolves in mouse spermatocyte meiosis
por: Eyster, Craig, et al.
Publicado: (2019)

Pericentromeric heterochromatin is hierarchically organized and spatially contacts H3K9me2 islands in euchromatin
por: Lee, Yuh Chwen G., et al.
Publicado: (2020)

Homologues of potato chromosome 5 show variable collinearity in the euchromatin, but dramatic absence of sequence similarity in the pericentromeric heterochromatin
por: de Boer, Jan M, et al.
Publicado: (2015)

H3K9 Promotes Under-Replication of Pericentromeric Heterochromatin in Drosophila Salivary Gland Polytene Chromosomes
por: Armstrong, Robin L., et al.
Publicado: (2019)

H3K27me3 at pericentromeric heterochromatin is a defining feature of the early mouse blastocyst
por: Pailles, Mélanie, et al.
Publicado: (2022)

Effects of Mutations in the Drosophila melanogaster Rif1 Gene on the Replication and Underreplication of Pericentromeric Heterochromatin in Salivary Gland Polytene Chromosomes
por: Kolesnikova, Tatyana D., et al.
Publicado: (2020)

Epigenetic reprogramming in pancreatic premalignancy and clinical implications
por: Zhang, Wei, et al.
Publicado: (2023)

Timely double-strand break repair and pathway choice in pericentromeric heterochromatin depend on the histone demethylase dKDM4A
por: Janssen, Aniek, et al.
Publicado: (2019)

The Cancer/Testis Antigen Gene VCX2 Is Rarely Expressed in Malignancies but Can Be Epigenetically Activated Using DNA Methyltransferase and Histone Deacetylase Inhibitors
por: Jakobsen, Mie K., et al.
Publicado: (2021)

SSX addiction in melanoma propagates tumor growth and metastasis
por: Traynor, Sofie, et al.
Publicado: (2022)

Pericentromere clustering in Tradescantia section Rhoeo involves self-associations of AT- and GC-rich heterochromatin fractions, is developmentally regulated, and increases during differentiation
por: Golczyk, Hieronim, et al.
Publicado: (2020)

Association of the interferon-β gene with pericentromeric heterochromatin is dynamically regulated during virus infection through a YY1-dependent mechanism
por: Josse, T., et al.
Publicado: (2012)

The role of GAGE cancer/testis antigen in metastasis: the jury is still out
por: Gjerstorff, Morten Frier, et al.
Publicado: (2016)

Epigenetic reprogramming and re-differentiation of a Ewing sarcoma cell line
por: Moore, Joseph B., et al.
Publicado: (2015)

Mammalian SWI/SNF Enzymes and the Epigenetics of Tumor Cell Metabolic Reprogramming
por: Nickerson, Jeffrey A., et al.
Publicado: (2017)

Common Features of the Pericentromere and Nucleolus
por: Lawrimore, Colleen J., et al.
Publicado: (2019)

A role for MED14 and UVH6 in heterochromatin transcription upon destabilization of silencing
por: Bourguet, Pierre, et al.
Publicado: (2018)

Heterochromatin establishment during early mammalian development is regulated by pericentromeric RNA and characterized by non-repressive H3K9me3
por: Burton, Adam, et al.
Publicado: (2020)

Heterochromatin: an epigenetic point of view in aging
por: Lee, Jong-Hyuk, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_13dsug2ebjt02hv12mpca6o15p