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Gonad dose assessment in paediatric kidney nuclear medicine test using Monte Carlo simulation
In this study, we evaluated the effect of radiation dose on gonads during paediatric kidney nuclear medicine tests. Using Monte Carlo simulations, the distribution and effects of radiation were physically evaluated by displaying the distribution path of the source in the human body over time. In par...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674698/ https://www.ncbi.nlm.nih.gov/pubmed/32930783 http://dx.doi.org/10.1093/jrr/rraa080 |
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author | Lee, Dong-Yeon Kye, Yong-Uk Kim, Hyo-Jin Kim, Jeung-Kee Kang, Yeong-Rok |
author_facet | Lee, Dong-Yeon Kye, Yong-Uk Kim, Hyo-Jin Kim, Jeung-Kee Kang, Yeong-Rok |
author_sort | Lee, Dong-Yeon |
collection | PubMed |
description | In this study, we evaluated the effect of radiation dose on gonads during paediatric kidney nuclear medicine tests. Using Monte Carlo simulations, the distribution and effects of radiation were physically evaluated by displaying the distribution path of the source in the human body over time. In particular, the evaluation of doses in children, who are sensitive to radiation during nuclear medicine tests that use internal exposure among several types of medical exposures, was conducted to obtain data for the management of medical exposures. Our results indicated that under normal kidney function, the dose received by the target kidney was 0.430 mGy/mCi, which is ~6% higher than the dose suggested by the International Commission on Radiation Protection (ICRP). Furthermore, when kidney function was compromised, the dose estimated was 0.726 mGy/mCi, which is ~2% lower than the dose suggested by the ICRP. In the male and female gonads, namely the testicles and ovaries, the doses received were 0.359 mGy/mCi and 0.394 mGy/mCi, respectively, under normal kidney function. Similarly, under abnormal kidney function, the doses ranged from 0.187 to 0.353 mGy/mCi and 0.238 to 0.388 mGy/mCi in the male and female gonads, respectively. |
format | Online Article Text |
id | pubmed-7674698 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-76746982020-11-24 Gonad dose assessment in paediatric kidney nuclear medicine test using Monte Carlo simulation Lee, Dong-Yeon Kye, Yong-Uk Kim, Hyo-Jin Kim, Jeung-Kee Kang, Yeong-Rok J Radiat Res Technical Report In this study, we evaluated the effect of radiation dose on gonads during paediatric kidney nuclear medicine tests. Using Monte Carlo simulations, the distribution and effects of radiation were physically evaluated by displaying the distribution path of the source in the human body over time. In particular, the evaluation of doses in children, who are sensitive to radiation during nuclear medicine tests that use internal exposure among several types of medical exposures, was conducted to obtain data for the management of medical exposures. Our results indicated that under normal kidney function, the dose received by the target kidney was 0.430 mGy/mCi, which is ~6% higher than the dose suggested by the International Commission on Radiation Protection (ICRP). Furthermore, when kidney function was compromised, the dose estimated was 0.726 mGy/mCi, which is ~2% lower than the dose suggested by the ICRP. In the male and female gonads, namely the testicles and ovaries, the doses received were 0.359 mGy/mCi and 0.394 mGy/mCi, respectively, under normal kidney function. Similarly, under abnormal kidney function, the doses ranged from 0.187 to 0.353 mGy/mCi and 0.238 to 0.388 mGy/mCi in the male and female gonads, respectively. Oxford University Press 2020-09-15 /pmc/articles/PMC7674698/ /pubmed/32930783 http://dx.doi.org/10.1093/jrr/rraa080 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of The Japanese Radiation Research Society and Japanese Society for Radiation Oncology. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Technical Report Lee, Dong-Yeon Kye, Yong-Uk Kim, Hyo-Jin Kim, Jeung-Kee Kang, Yeong-Rok Gonad dose assessment in paediatric kidney nuclear medicine test using Monte Carlo simulation |
title | Gonad dose assessment in paediatric kidney nuclear medicine test using Monte Carlo simulation |
title_full | Gonad dose assessment in paediatric kidney nuclear medicine test using Monte Carlo simulation |
title_fullStr | Gonad dose assessment in paediatric kidney nuclear medicine test using Monte Carlo simulation |
title_full_unstemmed | Gonad dose assessment in paediatric kidney nuclear medicine test using Monte Carlo simulation |
title_short | Gonad dose assessment in paediatric kidney nuclear medicine test using Monte Carlo simulation |
title_sort | gonad dose assessment in paediatric kidney nuclear medicine test using monte carlo simulation |
topic | Technical Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674698/ https://www.ncbi.nlm.nih.gov/pubmed/32930783 http://dx.doi.org/10.1093/jrr/rraa080 |
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