The frequency of POLE-mutation in endometrial carcinoma and prognostic implications: a systemic review and meta-analysis

BACKGROUND: Endometrial carcinoma (EC) is classified into four distinct molecular subgroups including ultramutated DNA polymerase epsilon (POLE). POLE-mutated tumors have the best prognosis and are a promising target for immunotherapy. This meta-analysis consolidated the reported variation of POLE-m...

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Detalles Bibliográficos
Autores principales: Jumaah, Alaa Salah, Salim, Mais Muhammed, Al-Haddad, Hawraa Sahib, McAllister, Katherine Ann, Yasseen, Akeel Abed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Pathologists and the Korean Society for Cytopathology 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674757/
https://www.ncbi.nlm.nih.gov/pubmed/32867011
http://dx.doi.org/10.4132/jptm.2020.07.23

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