Cargando…
CEP164 Deficiency Causes Hyperproliferation of Pancreatic Cancer Cells
Primary cilia are hair-like projections that protrude from most mammalian cells and mediate various extracellular signaling pathways. Pancreatic ductal adenocarcinoma (PDAC) cells are known to lose their primary cilia, but the relevance of this phenomenon remains unclear. In this study, we generated...
Autores principales: | Kobayashi, Tetsuo, Tanaka, Kosuke, Mashima, Yu, Shoda, Ayano, Tokuda, Mio, Itoh, Hiroshi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674857/ https://www.ncbi.nlm.nih.gov/pubmed/33251215 http://dx.doi.org/10.3389/fcell.2020.587691 |
Ejemplares similares
-
Smarca4 deficiency induces Pttg1 oncogene upregulation and hyperproliferation of tubular and interstitial cells during kidney development
por: Xu, Jinshu, et al.
Publicado: (2023) -
CEP250 is Required for Maintaining Centrosome Cohesion in the Germline and Fertility in Male Mice
por: Floriot, Sandrine, et al.
Publicado: (2022) -
Long-Read Sequencing to Unravel Complex Structural Variants of CEP78 Leading to Cone-Rod Dystrophy and Hearing Loss
por: Ascari, Giulia, et al.
Publicado: (2021) -
CEP78 functions downstream of CEP350 to control biogenesis of primary cilia by negatively regulating CP110 levels
por: Gonçalves, André Brás, et al.
Publicado: (2021) -
Embryonic and foetal expression patterns of the ciliopathy gene CEP164
por: Devlin, L. A., et al.
Publicado: (2020)