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The effect of ejection fraction on mortality in Coronary Artery Bypass Grafting (CABG) patients
BACKGROUND AND OBJECTIVES: Patients with low ejection fraction undergoing isolated CABG surgery are at a higher risk for postoperative complications and mortality. This study was conducted to evaluate the impact of ejection fraction on the outcome of isolated Coronary Artery Bypass Grafting (CABG)....
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Professional Medical Publications
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674905/ https://www.ncbi.nlm.nih.gov/pubmed/33235556 http://dx.doi.org/10.12669/pjms.36.7.3266 |
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author | Awan, Nabil Iftikhar Jan, Azam Rehman, Mujeeb Ur Ayaz, Narmeen |
author_facet | Awan, Nabil Iftikhar Jan, Azam Rehman, Mujeeb Ur Ayaz, Narmeen |
author_sort | Awan, Nabil Iftikhar |
collection | PubMed |
description | BACKGROUND AND OBJECTIVES: Patients with low ejection fraction undergoing isolated CABG surgery are at a higher risk for postoperative complications and mortality. This study was conducted to evaluate the impact of ejection fraction on the outcome of isolated Coronary Artery Bypass Grafting (CABG). METHODS: Between July, 2017 to May, 2019 total 1214 patients underwent isolated CABG. Patients were divided into three groups based on their pre-operative Ejection Fraction (EF). Group-I included 625 patients with EF >50% [Normal EF], Group-II included 484 patients with EF 35-50% [Mild to Moderately Reduced EF], and Group 3 included 105 patients with EF<35% [Severely Reduced EF]. RESULTS: The mean age of Group-I was 57.58 ± 9.206, Group-II was 58.38±9.124 and Group-III was 58.81± 8.663. The male gender was the predominant gender in all three groups: 194(41.1%) in Group-I, 201(52.6%) in Gp2, 52 (61.9%) in Group-III. 231(36.9) patients in Group-I, 234(48.3)in Group-II and 59(56.2) in Group-III had raised creatinine pre operatively. 5(0.8%) patients in Group-I, 2(0.4%) in Group-II and 3(2.9%) in Group-III had history of CVA. Hypertension was present in approximately 60% of all our patients. In the per-operative period 20(3.2%) patients in Group-I required an IABP as compared to 73(15.1%) in Group-II and 41(39.0%) in Group-III. The mean post-operative mortality in Group-I was 19 (3%), Group-II was 24(5.0%) and low EF group was 9(8.6%). CONCLUSIONS: The results clearly indicate that worsening pre-operative ejection fraction is associated with a higher mortality post-operatively in patients undergoing isolated CABG. In addition, use of IABP increases as pre-operative LVEF decreases. |
format | Online Article Text |
id | pubmed-7674905 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Professional Medical Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-76749052020-11-23 The effect of ejection fraction on mortality in Coronary Artery Bypass Grafting (CABG) patients Awan, Nabil Iftikhar Jan, Azam Rehman, Mujeeb Ur Ayaz, Narmeen Pak J Med Sci Original Article BACKGROUND AND OBJECTIVES: Patients with low ejection fraction undergoing isolated CABG surgery are at a higher risk for postoperative complications and mortality. This study was conducted to evaluate the impact of ejection fraction on the outcome of isolated Coronary Artery Bypass Grafting (CABG). METHODS: Between July, 2017 to May, 2019 total 1214 patients underwent isolated CABG. Patients were divided into three groups based on their pre-operative Ejection Fraction (EF). Group-I included 625 patients with EF >50% [Normal EF], Group-II included 484 patients with EF 35-50% [Mild to Moderately Reduced EF], and Group 3 included 105 patients with EF<35% [Severely Reduced EF]. RESULTS: The mean age of Group-I was 57.58 ± 9.206, Group-II was 58.38±9.124 and Group-III was 58.81± 8.663. The male gender was the predominant gender in all three groups: 194(41.1%) in Group-I, 201(52.6%) in Gp2, 52 (61.9%) in Group-III. 231(36.9) patients in Group-I, 234(48.3)in Group-II and 59(56.2) in Group-III had raised creatinine pre operatively. 5(0.8%) patients in Group-I, 2(0.4%) in Group-II and 3(2.9%) in Group-III had history of CVA. Hypertension was present in approximately 60% of all our patients. In the per-operative period 20(3.2%) patients in Group-I required an IABP as compared to 73(15.1%) in Group-II and 41(39.0%) in Group-III. The mean post-operative mortality in Group-I was 19 (3%), Group-II was 24(5.0%) and low EF group was 9(8.6%). CONCLUSIONS: The results clearly indicate that worsening pre-operative ejection fraction is associated with a higher mortality post-operatively in patients undergoing isolated CABG. In addition, use of IABP increases as pre-operative LVEF decreases. Professional Medical Publications 2020 /pmc/articles/PMC7674905/ /pubmed/33235556 http://dx.doi.org/10.12669/pjms.36.7.3266 Text en Copyright: © Pakistan Journal of Medical Sciences http://creativecommons.org/licenses/by/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Awan, Nabil Iftikhar Jan, Azam Rehman, Mujeeb Ur Ayaz, Narmeen The effect of ejection fraction on mortality in Coronary Artery Bypass Grafting (CABG) patients |
title | The effect of ejection fraction on mortality in Coronary Artery Bypass Grafting (CABG) patients |
title_full | The effect of ejection fraction on mortality in Coronary Artery Bypass Grafting (CABG) patients |
title_fullStr | The effect of ejection fraction on mortality in Coronary Artery Bypass Grafting (CABG) patients |
title_full_unstemmed | The effect of ejection fraction on mortality in Coronary Artery Bypass Grafting (CABG) patients |
title_short | The effect of ejection fraction on mortality in Coronary Artery Bypass Grafting (CABG) patients |
title_sort | effect of ejection fraction on mortality in coronary artery bypass grafting (cabg) patients |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674905/ https://www.ncbi.nlm.nih.gov/pubmed/33235556 http://dx.doi.org/10.12669/pjms.36.7.3266 |
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