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Supporting SARS-CoV-2 Papain-Like Protease Drug Discovery: In silico Methods and Benchmarking
The coronavirus disease 19 (COVID-19) is a rapidly growing pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Its papain-like protease (SARS-CoV-2 PLpro) is a crucial target to halt virus replication. SARS-CoV PLpro and SARS-CoV-2 PLpro share an 82.9% sequence ident...
Autores principales: | Ibrahim, Tamer M., Ismail, Muhammad I., Bauer, Matthias R., Bekhit, Adnan A., Boeckler, Frank M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674952/ https://www.ncbi.nlm.nih.gov/pubmed/33251185 http://dx.doi.org/10.3389/fchem.2020.592289 |
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