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Comprehensive Proteomic Profiling of Urinary Exosomes and Identification of Potential Non-invasive Early Biomarkers of Alzheimer’s Disease in 5XFAD Mouse Model
BACKGROUND: Alzheimer’s disease (AD) is an incurable neurodegenerative disease characterized by irreversible progressive cognitive deficits. Identification of candidate biomarkers, before amyloid-β-plaque deposition occurs, is therefore of great importance for early intervention of AD. OBJECTIVE: To...
Autores principales: | Song, Zhiqi, Xu, Yanfeng, Zhang, Ling, Zhou, Li, Zhang, Yu, Han, Yunlin, Li, Xianglei, Yu, Pin, Qu, Yajin, Zhao, Wenjie, Qin, Chuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674956/ https://www.ncbi.nlm.nih.gov/pubmed/33250918 http://dx.doi.org/10.3389/fgene.2020.565479 |
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