Atrial Fibrillation Structural Substrates: Aetiology, Identification and Implications

Atrial remodelling in AF underlines the electrical, structural and mechanical changes in the atria of patients with AF. Several risk factors for AF contribute to the development of the atrial substrate, with some evidence that atrial remodelling reversal is possible with targeted intervention. In th...

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Autores principales: Al-Kaisey, Ahmed M, Parameswaran, Ramanathan, Kalman, Jonathan M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Radcliffe Cardiology 2020
Materias:
Electrophysiology and Ablation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7675137/
https://www.ncbi.nlm.nih.gov/pubmed/33240506
http://dx.doi.org/10.15420/aer.2020.19
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author Al-Kaisey, Ahmed M
Parameswaran, Ramanathan
Kalman, Jonathan M
author_facet Al-Kaisey, Ahmed M
Parameswaran, Ramanathan
Kalman, Jonathan M
author_sort Al-Kaisey, Ahmed M
collection PubMed
description Atrial remodelling in AF underlines the electrical, structural and mechanical changes in the atria of patients with AF. Several risk factors for AF contribute to the development of the atrial substrate, with some evidence that atrial remodelling reversal is possible with targeted intervention. In this article, the authors review the electrophysiological changes that characterise the atrial substrate in patients with AF risk factors. They also discuss the pitfalls of mapping the atrial substrate and the implications for developing tailored ablation strategies to improve outcomes in patients with AF.
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spelling pubmed-76751372020-11-24 Atrial Fibrillation Structural Substrates: Aetiology, Identification and Implications Al-Kaisey, Ahmed M Parameswaran, Ramanathan Kalman, Jonathan M Arrhythm Electrophysiol Rev Electrophysiology and Ablation Atrial remodelling in AF underlines the electrical, structural and mechanical changes in the atria of patients with AF. Several risk factors for AF contribute to the development of the atrial substrate, with some evidence that atrial remodelling reversal is possible with targeted intervention. In this article, the authors review the electrophysiological changes that characterise the atrial substrate in patients with AF risk factors. They also discuss the pitfalls of mapping the atrial substrate and the implications for developing tailored ablation strategies to improve outcomes in patients with AF. Radcliffe Cardiology 2020-11 /pmc/articles/PMC7675137/ /pubmed/33240506 http://dx.doi.org/10.15420/aer.2020.19 Text en Copyright © 2020, Radcliffe Cardiology https://creativecommons.org/licenses/by-nc/4.0/legalcode This work is open access under the CC-BY-NC 4.0 License which allows users to copy, redistribute and make derivative works for non-commercial purposes, provided the original work is cited correctly.
spellingShingle Electrophysiology and Ablation
Al-Kaisey, Ahmed M
Parameswaran, Ramanathan
Kalman, Jonathan M
Atrial Fibrillation Structural Substrates: Aetiology, Identification and Implications
title Atrial Fibrillation Structural Substrates: Aetiology, Identification and Implications
title_full Atrial Fibrillation Structural Substrates: Aetiology, Identification and Implications
title_fullStr Atrial Fibrillation Structural Substrates: Aetiology, Identification and Implications
title_full_unstemmed Atrial Fibrillation Structural Substrates: Aetiology, Identification and Implications
title_short Atrial Fibrillation Structural Substrates: Aetiology, Identification and Implications
title_sort atrial fibrillation structural substrates: aetiology, identification and implications
topic Electrophysiology and Ablation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7675137/
https://www.ncbi.nlm.nih.gov/pubmed/33240506
http://dx.doi.org/10.15420/aer.2020.19
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AT parameswaranramanathan atrialfibrillationstructuralsubstratesaetiologyidentificationandimplications
AT kalmanjonathanm atrialfibrillationstructuralsubstratesaetiologyidentificationandimplications

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