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COVID‐19 and the pulmonary complications of sickle cell disease
Sickle cell disease (SCD) patients are commonly affected by pulmonary complications such as acute chest syndrome (ACS), pulmonary embolism (PE) and pneumonia that contribute to significant mortality risks. With a greater susceptibility to infection, they are deemed to be vulnerable patients during t...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7675298/ https://www.ncbi.nlm.nih.gov/pubmed/33230510 http://dx.doi.org/10.1002/jha2.105 |
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author | Sivalingam, Thivya Inusa, Baba Doyle, Pat Oteng‐Ntim, Eugene |
author_facet | Sivalingam, Thivya Inusa, Baba Doyle, Pat Oteng‐Ntim, Eugene |
author_sort | Sivalingam, Thivya |
collection | PubMed |
description | Sickle cell disease (SCD) patients are commonly affected by pulmonary complications such as acute chest syndrome (ACS), pulmonary embolism (PE) and pneumonia that contribute to significant mortality risks. With a greater susceptibility to infection, they are deemed to be vulnerable patients during the current COVID‐19 pandemic. In emerging small case studies of SCD patients with COVID‐19 and further complicated by pneumonia, ACS, and/or PE, the clinical benefits of early exchange transfusion and Tocilizumab are evident. However, further clinical trials and larger cohort studies are essential to evaluate effective diagnostic and management options for this high‐risk group. |
format | Online Article Text |
id | pubmed-7675298 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-76752982020-11-19 COVID‐19 and the pulmonary complications of sickle cell disease Sivalingam, Thivya Inusa, Baba Doyle, Pat Oteng‐Ntim, Eugene EJHaem Short Reports Sickle cell disease (SCD) patients are commonly affected by pulmonary complications such as acute chest syndrome (ACS), pulmonary embolism (PE) and pneumonia that contribute to significant mortality risks. With a greater susceptibility to infection, they are deemed to be vulnerable patients during the current COVID‐19 pandemic. In emerging small case studies of SCD patients with COVID‐19 and further complicated by pneumonia, ACS, and/or PE, the clinical benefits of early exchange transfusion and Tocilizumab are evident. However, further clinical trials and larger cohort studies are essential to evaluate effective diagnostic and management options for this high‐risk group. John Wiley and Sons Inc. 2020-10-08 /pmc/articles/PMC7675298/ /pubmed/33230510 http://dx.doi.org/10.1002/jha2.105 Text en © 2020 The Authors. eJHaem published by British Society for Haematology and John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Short Reports Sivalingam, Thivya Inusa, Baba Doyle, Pat Oteng‐Ntim, Eugene COVID‐19 and the pulmonary complications of sickle cell disease |
title | COVID‐19 and the pulmonary complications of sickle cell disease |
title_full | COVID‐19 and the pulmonary complications of sickle cell disease |
title_fullStr | COVID‐19 and the pulmonary complications of sickle cell disease |
title_full_unstemmed | COVID‐19 and the pulmonary complications of sickle cell disease |
title_short | COVID‐19 and the pulmonary complications of sickle cell disease |
title_sort | covid‐19 and the pulmonary complications of sickle cell disease |
topic | Short Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7675298/ https://www.ncbi.nlm.nih.gov/pubmed/33230510 http://dx.doi.org/10.1002/jha2.105 |
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