Inactivation of CES1 Blocks Prostaglandin D(2) Glyceryl Ester Catabolism in Monocytes/Macrophages and Enhances Its Anti-inflammatory Effects, Whereas the Pro-inflammatory Effects of Prostaglandin E(2) Glyceryl Ester Are Attenuated

[Image: see text] Human monocytic cells in blood have important roles in host defense and express the enzyme carboxylesterase 1 (CES1). This metabolic serine hydrolase plays a critical role in the metabolism of many molecules, including lipid mediators called prostaglandin glyceryl esters (PG-Gs), w...

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Detalles Bibliográficos
Autores principales: Scheaffer, Hannah L., Borazjani, Abdolsamad, Szafran, Brittany N., Ross, Matthew K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7675540/
https://www.ncbi.nlm.nih.gov/pubmed/33225149
http://dx.doi.org/10.1021/acsomega.0c03961

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7675540/
https://www.ncbi.nlm.nih.gov/pubmed/33225149
http://dx.doi.org/10.1021/acsomega.0c03961

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