Liver transplantation in a patient after COVID-19 – Rapid loss of antibodies and prolonged viral RNA shedding

To date, little is known about the duration and effectiveness of immunity as well as possible adverse late effects after an infection with SARS-CoV-2. Thus it is unclear, when and if liver transplantation can be safely offered to patients who suffered from COVID-19. Here, we report on a successful l...

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Autores principales: Niess, Hanno, Börner, Nikolaus, Muenchhoff, Maximilian, Khatamzas, Elham, Stangl, Manfred, Graf, Alex, Girl, Philipp, Georgi, Enrico, Koliogiannis, Dionysios, Denk, Gerald, Irlbeck, Michael, Werner, Jens, Guba, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Transplantation & American Society of Transplant Surgeons. Published by Elsevier Inc. 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7675727/
https://www.ncbi.nlm.nih.gov/pubmed/33047475
http://dx.doi.org/10.1111/ajt.16349
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author Niess, Hanno
Börner, Nikolaus
Muenchhoff, Maximilian
Khatamzas, Elham
Stangl, Manfred
Graf, Alex
Girl, Philipp
Georgi, Enrico
Koliogiannis, Dionysios
Denk, Gerald
Irlbeck, Michael
Werner, Jens
Guba, Markus
author_facet Niess, Hanno
Börner, Nikolaus
Muenchhoff, Maximilian
Khatamzas, Elham
Stangl, Manfred
Graf, Alex
Girl, Philipp
Georgi, Enrico
Koliogiannis, Dionysios
Denk, Gerald
Irlbeck, Michael
Werner, Jens
Guba, Markus
author_sort Niess, Hanno
collection PubMed
description To date, little is known about the duration and effectiveness of immunity as well as possible adverse late effects after an infection with SARS-CoV-2. Thus it is unclear, when and if liver transplantation can be safely offered to patients who suffered from COVID-19. Here, we report on a successful liver transplantation shortly after convalescence from COVID-19 with subsequent partial seroreversion as well as recurrence and prolonged shedding of viral RNA.
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spelling pubmed-76757272020-11-19 Liver transplantation in a patient after COVID-19 – Rapid loss of antibodies and prolonged viral RNA shedding Niess, Hanno Börner, Nikolaus Muenchhoff, Maximilian Khatamzas, Elham Stangl, Manfred Graf, Alex Girl, Philipp Georgi, Enrico Koliogiannis, Dionysios Denk, Gerald Irlbeck, Michael Werner, Jens Guba, Markus Am J Transplant Case Report To date, little is known about the duration and effectiveness of immunity as well as possible adverse late effects after an infection with SARS-CoV-2. Thus it is unclear, when and if liver transplantation can be safely offered to patients who suffered from COVID-19. Here, we report on a successful liver transplantation shortly after convalescence from COVID-19 with subsequent partial seroreversion as well as recurrence and prolonged shedding of viral RNA. American Society of Transplantation & American Society of Transplant Surgeons. Published by Elsevier Inc. 2021-04 2022-12-30 /pmc/articles/PMC7675727/ /pubmed/33047475 http://dx.doi.org/10.1111/ajt.16349 Text en Copyright © 2021 American Society of Transplantation & American Society of Transplant Surgeons. Published by Elsevier Inc. All rights reserved. Published by Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Case Report
Niess, Hanno
Börner, Nikolaus
Muenchhoff, Maximilian
Khatamzas, Elham
Stangl, Manfred
Graf, Alex
Girl, Philipp
Georgi, Enrico
Koliogiannis, Dionysios
Denk, Gerald
Irlbeck, Michael
Werner, Jens
Guba, Markus
Liver transplantation in a patient after COVID-19 – Rapid loss of antibodies and prolonged viral RNA shedding
title Liver transplantation in a patient after COVID-19 – Rapid loss of antibodies and prolonged viral RNA shedding
title_full Liver transplantation in a patient after COVID-19 – Rapid loss of antibodies and prolonged viral RNA shedding
title_fullStr Liver transplantation in a patient after COVID-19 – Rapid loss of antibodies and prolonged viral RNA shedding
title_full_unstemmed Liver transplantation in a patient after COVID-19 – Rapid loss of antibodies and prolonged viral RNA shedding
title_short Liver transplantation in a patient after COVID-19 – Rapid loss of antibodies and prolonged viral RNA shedding
title_sort liver transplantation in a patient after covid-19 – rapid loss of antibodies and prolonged viral rna shedding
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7675727/
https://www.ncbi.nlm.nih.gov/pubmed/33047475
http://dx.doi.org/10.1111/ajt.16349
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