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Fulminant myocarditis in a patient with coronavirus disease 2019 and rapid myocardial recovery following treatment

Coronavirus disease 2019 (COVID‐19) is a global pandemic increasingly encountered in the clinical setting. It typically manifests as a respiratory illness, although cardiac involvement is common and portends a worse prognosis. We present the case of a 56‐year‐old male admitted with COVID‐19 fulminan...

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Autores principales: Gay, Hawkins C., Sinha, Arjun, Michel, Eriberto, Mozer, Anthony B., Budd, Ashley, Feinstein, Matthew J., Benzuly, Keith H., Al‐Qamari, Abbas, Pawale, Amit A., Vorovich, Esther E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7675750/
https://www.ncbi.nlm.nih.gov/pubmed/33063450
http://dx.doi.org/10.1002/ehf2.13041
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author Gay, Hawkins C.
Sinha, Arjun
Michel, Eriberto
Mozer, Anthony B.
Budd, Ashley
Feinstein, Matthew J.
Benzuly, Keith H.
Al‐Qamari, Abbas
Pawale, Amit A.
Vorovich, Esther E.
author_facet Gay, Hawkins C.
Sinha, Arjun
Michel, Eriberto
Mozer, Anthony B.
Budd, Ashley
Feinstein, Matthew J.
Benzuly, Keith H.
Al‐Qamari, Abbas
Pawale, Amit A.
Vorovich, Esther E.
author_sort Gay, Hawkins C.
collection PubMed
description Coronavirus disease 2019 (COVID‐19) is a global pandemic increasingly encountered in the clinical setting. It typically manifests as a respiratory illness, although cardiac involvement is common and portends a worse prognosis. We present the case of a 56‐year‐old male admitted with COVID‐19 fulminant myocarditis and cardiogenic shock. We discuss important aspects of the multidisciplinary and interventional care involved in treating cardiogenic shock as well as the likely mechanisms of, and potential treatment for, COVID‐19 myocarditis. The various pathways of myocardial injury, including direct viral damage, macrophage activation, and lymphocytic infiltration, are outlined in detail in addition to associated pathology such as cytokine release syndrome. COVID‐19 is a complex and multisystem disease process; in addition to supportive care, specific consideration should be given to the underlying mechanism of injury for each patient.
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spelling pubmed-76757502020-11-19 Fulminant myocarditis in a patient with coronavirus disease 2019 and rapid myocardial recovery following treatment Gay, Hawkins C. Sinha, Arjun Michel, Eriberto Mozer, Anthony B. Budd, Ashley Feinstein, Matthew J. Benzuly, Keith H. Al‐Qamari, Abbas Pawale, Amit A. Vorovich, Esther E. ESC Heart Fail Case Reports Coronavirus disease 2019 (COVID‐19) is a global pandemic increasingly encountered in the clinical setting. It typically manifests as a respiratory illness, although cardiac involvement is common and portends a worse prognosis. We present the case of a 56‐year‐old male admitted with COVID‐19 fulminant myocarditis and cardiogenic shock. We discuss important aspects of the multidisciplinary and interventional care involved in treating cardiogenic shock as well as the likely mechanisms of, and potential treatment for, COVID‐19 myocarditis. The various pathways of myocardial injury, including direct viral damage, macrophage activation, and lymphocytic infiltration, are outlined in detail in addition to associated pathology such as cytokine release syndrome. COVID‐19 is a complex and multisystem disease process; in addition to supportive care, specific consideration should be given to the underlying mechanism of injury for each patient. John Wiley and Sons Inc. 2020-10-15 /pmc/articles/PMC7675750/ /pubmed/33063450 http://dx.doi.org/10.1002/ehf2.13041 Text en © 2020 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of the European Society of Cardiology This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Reports
Gay, Hawkins C.
Sinha, Arjun
Michel, Eriberto
Mozer, Anthony B.
Budd, Ashley
Feinstein, Matthew J.
Benzuly, Keith H.
Al‐Qamari, Abbas
Pawale, Amit A.
Vorovich, Esther E.
Fulminant myocarditis in a patient with coronavirus disease 2019 and rapid myocardial recovery following treatment
title Fulminant myocarditis in a patient with coronavirus disease 2019 and rapid myocardial recovery following treatment
title_full Fulminant myocarditis in a patient with coronavirus disease 2019 and rapid myocardial recovery following treatment
title_fullStr Fulminant myocarditis in a patient with coronavirus disease 2019 and rapid myocardial recovery following treatment
title_full_unstemmed Fulminant myocarditis in a patient with coronavirus disease 2019 and rapid myocardial recovery following treatment
title_short Fulminant myocarditis in a patient with coronavirus disease 2019 and rapid myocardial recovery following treatment
title_sort fulminant myocarditis in a patient with coronavirus disease 2019 and rapid myocardial recovery following treatment
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7675750/
https://www.ncbi.nlm.nih.gov/pubmed/33063450
http://dx.doi.org/10.1002/ehf2.13041
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