Radiotherapy for malignant melanoma of the lacrimal sac

Malignant melanoma of the lacrimal sac is an exceptionally rare tumor with a poor prognosis. We report two cases of malignant melanoma of the lacrimal sac: a 73 year-old female treated with primary surgical resection and a 75 year-old male treated with surgical resection, adjuvant proton beam radiot...

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Detalles Bibliográficos
Autores principales: Cheng, Tiffany W, Yu, Nathan Y, Seetharam, Mahesh, Patel, Samir H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7675887/
https://www.ncbi.nlm.nih.gov/pubmed/33240474
http://dx.doi.org/10.1177/2036361320971943
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author Cheng, Tiffany W
Yu, Nathan Y
Seetharam, Mahesh
Patel, Samir H
author_facet Cheng, Tiffany W
Yu, Nathan Y
Seetharam, Mahesh
Patel, Samir H
author_sort Cheng, Tiffany W
collection PubMed
description Malignant melanoma of the lacrimal sac is an exceptionally rare tumor with a poor prognosis. We report two cases of malignant melanoma of the lacrimal sac: a 73 year-old female treated with primary surgical resection and a 75 year-old male treated with surgical resection, adjuvant proton beam radiotherapy, and adjuvant immunotherapy. We discuss the role of post-operative proton beam therapy and recent advancements in immunotherapy. These cases highlight the importance of early diagnosis and multi-modality treatment in this aggressive malignancy.
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spelling pubmed-76758872020-11-24 Radiotherapy for malignant melanoma of the lacrimal sac Cheng, Tiffany W Yu, Nathan Y Seetharam, Mahesh Patel, Samir H Rare Tumors Case Report Malignant melanoma of the lacrimal sac is an exceptionally rare tumor with a poor prognosis. We report two cases of malignant melanoma of the lacrimal sac: a 73 year-old female treated with primary surgical resection and a 75 year-old male treated with surgical resection, adjuvant proton beam radiotherapy, and adjuvant immunotherapy. We discuss the role of post-operative proton beam therapy and recent advancements in immunotherapy. These cases highlight the importance of early diagnosis and multi-modality treatment in this aggressive malignancy. SAGE Publications 2020-11-11 /pmc/articles/PMC7675887/ /pubmed/33240474 http://dx.doi.org/10.1177/2036361320971943 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Cheng, Tiffany W
Yu, Nathan Y
Seetharam, Mahesh
Patel, Samir H
Radiotherapy for malignant melanoma of the lacrimal sac
title Radiotherapy for malignant melanoma of the lacrimal sac
title_full Radiotherapy for malignant melanoma of the lacrimal sac
title_fullStr Radiotherapy for malignant melanoma of the lacrimal sac
title_full_unstemmed Radiotherapy for malignant melanoma of the lacrimal sac
title_short Radiotherapy for malignant melanoma of the lacrimal sac
title_sort radiotherapy for malignant melanoma of the lacrimal sac
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7675887/
https://www.ncbi.nlm.nih.gov/pubmed/33240474
http://dx.doi.org/10.1177/2036361320971943
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AT yunathany radiotherapyformalignantmelanomaofthelacrimalsac
AT seetharammahesh radiotherapyformalignantmelanomaofthelacrimalsac
AT patelsamirh radiotherapyformalignantmelanomaofthelacrimalsac

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