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Occurrence and risks of antibiotics in an urban river in northeastern Tibetan Plateau

There is a dearth of information on the occurrence and risks of antibiotics in the urban rivers from plateau areas. This study investigated 83 antibiotics in water and sediments of an urban river and effluents of sewage treatment plants (E-STPs) in Xining, Qinghai (northeastern Tibetan Plateau). Fif...

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Autores principales: Kuang, Yuzhu, Guo, Xiaoyu, Hu, Jingrun, Li, Si, Zhang, Ruijie, Gao, Qiang, Yang, Xi, Chen, Qian, Sun, Weiling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7675971/
https://www.ncbi.nlm.nih.gov/pubmed/33208822
http://dx.doi.org/10.1038/s41598-020-77152-5
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author Kuang, Yuzhu
Guo, Xiaoyu
Hu, Jingrun
Li, Si
Zhang, Ruijie
Gao, Qiang
Yang, Xi
Chen, Qian
Sun, Weiling
author_facet Kuang, Yuzhu
Guo, Xiaoyu
Hu, Jingrun
Li, Si
Zhang, Ruijie
Gao, Qiang
Yang, Xi
Chen, Qian
Sun, Weiling
author_sort Kuang, Yuzhu
collection PubMed
description There is a dearth of information on the occurrence and risks of antibiotics in the urban rivers from plateau areas. This study investigated 83 antibiotics in water and sediments of an urban river and effluents of sewage treatment plants (E-STPs) in Xining, Qinghai (northeastern Tibetan Plateau). Fifty-three antibiotics were detected, and the concentrations of individual antibiotics varied in the range of undetected (ND)-552 ng/L in water, ND-164 ng/g in sediments, and ND-3821 ng/L in E-STPs. Seasonal differences of antibiotic concentrations were significant for water samples (p < 0.05) but insignificant for sediments (p > 0.05). In urban area, E-STP is the main source of antibiotics in the river, while runoff from manured cropland contributes partially to antibiotics in the river in the suburban area. The antibiotic compositions in water were different from those in sediments, but were similar to those in E-STPs. Notably, because of strong solar radiation and long sunshine hours in the plateau area, low levels of quinolones, which are sensitive to photolysis, were observed in river water. Moreover, norfloxacin and enrofloxacin, observed in urban river from other regions of China, were not detected in the Huangshui River water. The occurrence of ofloxacin, erythromycin, roxithromycin, clarithromycin, and trimethoprim in E-STPs may induce a possible risk to antibiotic resistance evolution. Trimethoprim, anhydroerythromycin, sulfamethoxazole, sulfapyridine, and clindamycin in river water could pose low to medium risks to aquatic organisms. Further investigation on the occurrence and distribution of antibiotic resistance genes in the Huangshui River is urgently needed.
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spelling pubmed-76759712020-11-19 Occurrence and risks of antibiotics in an urban river in northeastern Tibetan Plateau Kuang, Yuzhu Guo, Xiaoyu Hu, Jingrun Li, Si Zhang, Ruijie Gao, Qiang Yang, Xi Chen, Qian Sun, Weiling Sci Rep Article There is a dearth of information on the occurrence and risks of antibiotics in the urban rivers from plateau areas. This study investigated 83 antibiotics in water and sediments of an urban river and effluents of sewage treatment plants (E-STPs) in Xining, Qinghai (northeastern Tibetan Plateau). Fifty-three antibiotics were detected, and the concentrations of individual antibiotics varied in the range of undetected (ND)-552 ng/L in water, ND-164 ng/g in sediments, and ND-3821 ng/L in E-STPs. Seasonal differences of antibiotic concentrations were significant for water samples (p < 0.05) but insignificant for sediments (p > 0.05). In urban area, E-STP is the main source of antibiotics in the river, while runoff from manured cropland contributes partially to antibiotics in the river in the suburban area. The antibiotic compositions in water were different from those in sediments, but were similar to those in E-STPs. Notably, because of strong solar radiation and long sunshine hours in the plateau area, low levels of quinolones, which are sensitive to photolysis, were observed in river water. Moreover, norfloxacin and enrofloxacin, observed in urban river from other regions of China, were not detected in the Huangshui River water. The occurrence of ofloxacin, erythromycin, roxithromycin, clarithromycin, and trimethoprim in E-STPs may induce a possible risk to antibiotic resistance evolution. Trimethoprim, anhydroerythromycin, sulfamethoxazole, sulfapyridine, and clindamycin in river water could pose low to medium risks to aquatic organisms. Further investigation on the occurrence and distribution of antibiotic resistance genes in the Huangshui River is urgently needed. Nature Publishing Group UK 2020-11-18 /pmc/articles/PMC7675971/ /pubmed/33208822 http://dx.doi.org/10.1038/s41598-020-77152-5 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Kuang, Yuzhu
Guo, Xiaoyu
Hu, Jingrun
Li, Si
Zhang, Ruijie
Gao, Qiang
Yang, Xi
Chen, Qian
Sun, Weiling
Occurrence and risks of antibiotics in an urban river in northeastern Tibetan Plateau
title Occurrence and risks of antibiotics in an urban river in northeastern Tibetan Plateau
title_full Occurrence and risks of antibiotics in an urban river in northeastern Tibetan Plateau
title_fullStr Occurrence and risks of antibiotics in an urban river in northeastern Tibetan Plateau
title_full_unstemmed Occurrence and risks of antibiotics in an urban river in northeastern Tibetan Plateau
title_short Occurrence and risks of antibiotics in an urban river in northeastern Tibetan Plateau
title_sort occurrence and risks of antibiotics in an urban river in northeastern tibetan plateau
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7675971/
https://www.ncbi.nlm.nih.gov/pubmed/33208822
http://dx.doi.org/10.1038/s41598-020-77152-5
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