Endogenous antisense RNA curbs CD39 expression in Crohn’s disease

CD39 is an ectonucleotidase that initiates conversion of extracellular nucleotides into immunosuppressive adenosine. CD39 is expressed by regulatory T (Treg)-cells, where it mediates immunosuppression, and by a subset of T-helper (Th) 17-cells, where it limits pathogenicity. CD39 is regulated via si...

Descripción completa

Detalles Bibliográficos
Autores principales: Harshe, Rasika P., Xie, Anyan, Vuerich, Marta, Frank, Luiza Abrahão, Gromova, Barbora, Zhang, Haohai, Robles, Rene’ J., Mukherjee, Samiran, Csizmadia, Eva, Kokkotou, Efi, Cheifetz, Adam S., Moss, Alan C., Kota, Satya K., Robson, Simon C., Longhi, Maria Serena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7676266/
https://www.ncbi.nlm.nih.gov/pubmed/33208731
http://dx.doi.org/10.1038/s41467-020-19692-y

Ejemplares similares

Ejemplares similares