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Guidance on nebulization during the current COVID-19 pandemic
Awareness of the risk of airborne transmission of SARS-CoV-2 makes patients hesitant about using inhaled medications that are considered as a potential source of viral transmission and immunosuppression. However, patients with asthma or COPD should continue all prescribed inhaled medications. Appare...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7676318/ https://www.ncbi.nlm.nih.gov/pubmed/33248363 http://dx.doi.org/10.1016/j.rmed.2020.106236 |
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author | Cazzola, Mario Ora, Josuel Bianco, Andrea Rogliani, Paola Matera, Maria Gabriella |
author_facet | Cazzola, Mario Ora, Josuel Bianco, Andrea Rogliani, Paola Matera, Maria Gabriella |
author_sort | Cazzola, Mario |
collection | PubMed |
description | Awareness of the risk of airborne transmission of SARS-CoV-2 makes patients hesitant about using inhaled medications that are considered as a potential source of viral transmission and immunosuppression. However, patients with asthma or COPD should continue all prescribed inhaled medications. Apparently, inhalers, including pMDIs, DPIs, or SMIs, have a low risk of contamination although characteristics of drug formulation can precipitate cough, whereas some researchers do not rule out the probability that nebulizer treatments may increase the risk of infection transmission via droplet nuclei and aerosols. Considering that aerosol therapy generates fugitive emissions that are not inhaled by the patient and are released from the device during expiration, several international professional bodies have provided recommendations for drug delivery via inhalers and in particular, nebulizers. Unfortunately, these recommendations are often in conflict with each other and do not clarify whether it is appropriate to use nebulizers during this COVID-19 pandemic. Considering what is available in literature, there are no known infection-related hazards to an uninfected patient and also a patient with COVID-19 that preclude the use of a nebulizer at home, but it fundamental that all patients, regardless of whether or not suffering from COVID-19, always follow some practical advices. |
format | Online Article Text |
id | pubmed-7676318 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-76763182020-11-20 Guidance on nebulization during the current COVID-19 pandemic Cazzola, Mario Ora, Josuel Bianco, Andrea Rogliani, Paola Matera, Maria Gabriella Respir Med Short Review Awareness of the risk of airborne transmission of SARS-CoV-2 makes patients hesitant about using inhaled medications that are considered as a potential source of viral transmission and immunosuppression. However, patients with asthma or COPD should continue all prescribed inhaled medications. Apparently, inhalers, including pMDIs, DPIs, or SMIs, have a low risk of contamination although characteristics of drug formulation can precipitate cough, whereas some researchers do not rule out the probability that nebulizer treatments may increase the risk of infection transmission via droplet nuclei and aerosols. Considering that aerosol therapy generates fugitive emissions that are not inhaled by the patient and are released from the device during expiration, several international professional bodies have provided recommendations for drug delivery via inhalers and in particular, nebulizers. Unfortunately, these recommendations are often in conflict with each other and do not clarify whether it is appropriate to use nebulizers during this COVID-19 pandemic. Considering what is available in literature, there are no known infection-related hazards to an uninfected patient and also a patient with COVID-19 that preclude the use of a nebulizer at home, but it fundamental that all patients, regardless of whether or not suffering from COVID-19, always follow some practical advices. Elsevier Ltd. 2021-01 2020-11-19 /pmc/articles/PMC7676318/ /pubmed/33248363 http://dx.doi.org/10.1016/j.rmed.2020.106236 Text en © 2020 Elsevier Ltd. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Short Review Cazzola, Mario Ora, Josuel Bianco, Andrea Rogliani, Paola Matera, Maria Gabriella Guidance on nebulization during the current COVID-19 pandemic |
title | Guidance on nebulization during the current COVID-19 pandemic |
title_full | Guidance on nebulization during the current COVID-19 pandemic |
title_fullStr | Guidance on nebulization during the current COVID-19 pandemic |
title_full_unstemmed | Guidance on nebulization during the current COVID-19 pandemic |
title_short | Guidance on nebulization during the current COVID-19 pandemic |
title_sort | guidance on nebulization during the current covid-19 pandemic |
topic | Short Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7676318/ https://www.ncbi.nlm.nih.gov/pubmed/33248363 http://dx.doi.org/10.1016/j.rmed.2020.106236 |
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