Field Evaluation of Cholkit Rapid Diagnostic Test for Vibrio Cholerae O1 During a Cholera Outbreak in Malawi, 2018

Rapid diagnostic tests (RDTs) for cholera are an important emerging tool for surveillance, yet the currently available tests have several limitations. We assess the performance of a new RDT, Cholkit, during a cholera outbreak in Malawi compared with culture and find a sensitivity of 93.0% (95% CI, 8...

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Detalles Bibliográficos
Autores principales: Chibwe, Innocent, Kasambara, Watipaso, Kagoli, Mathews, Milala, Harry, Gondwe, Charity, Azman, Andrew S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7676503/
https://www.ncbi.nlm.nih.gov/pubmed/33241067
http://dx.doi.org/10.1093/ofid/ofaa493
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author Chibwe, Innocent
Kasambara, Watipaso
Kagoli, Mathews
Milala, Harry
Gondwe, Charity
Azman, Andrew S
author_facet Chibwe, Innocent
Kasambara, Watipaso
Kagoli, Mathews
Milala, Harry
Gondwe, Charity
Azman, Andrew S
author_sort Chibwe, Innocent
collection PubMed
description Rapid diagnostic tests (RDTs) for cholera are an important emerging tool for surveillance, yet the currently available tests have several limitations. We assess the performance of a new RDT, Cholkit, during a cholera outbreak in Malawi compared with culture and find a sensitivity of 93.0% (95% CI, 83.0%–98.1%) and a specificity of 95.7% (95% CI, 78.1%–100.0%).
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spelling pubmed-76765032020-11-24 Field Evaluation of Cholkit Rapid Diagnostic Test for Vibrio Cholerae O1 During a Cholera Outbreak in Malawi, 2018 Chibwe, Innocent Kasambara, Watipaso Kagoli, Mathews Milala, Harry Gondwe, Charity Azman, Andrew S Open Forum Infect Dis Brief Reports Rapid diagnostic tests (RDTs) for cholera are an important emerging tool for surveillance, yet the currently available tests have several limitations. We assess the performance of a new RDT, Cholkit, during a cholera outbreak in Malawi compared with culture and find a sensitivity of 93.0% (95% CI, 83.0%–98.1%) and a specificity of 95.7% (95% CI, 78.1%–100.0%). Oxford University Press 2020-10-16 /pmc/articles/PMC7676503/ /pubmed/33241067 http://dx.doi.org/10.1093/ofid/ofaa493 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Reports
Chibwe, Innocent
Kasambara, Watipaso
Kagoli, Mathews
Milala, Harry
Gondwe, Charity
Azman, Andrew S
Field Evaluation of Cholkit Rapid Diagnostic Test for Vibrio Cholerae O1 During a Cholera Outbreak in Malawi, 2018
title Field Evaluation of Cholkit Rapid Diagnostic Test for Vibrio Cholerae O1 During a Cholera Outbreak in Malawi, 2018
title_full Field Evaluation of Cholkit Rapid Diagnostic Test for Vibrio Cholerae O1 During a Cholera Outbreak in Malawi, 2018
title_fullStr Field Evaluation of Cholkit Rapid Diagnostic Test for Vibrio Cholerae O1 During a Cholera Outbreak in Malawi, 2018
title_full_unstemmed Field Evaluation of Cholkit Rapid Diagnostic Test for Vibrio Cholerae O1 During a Cholera Outbreak in Malawi, 2018
title_short Field Evaluation of Cholkit Rapid Diagnostic Test for Vibrio Cholerae O1 During a Cholera Outbreak in Malawi, 2018
title_sort field evaluation of cholkit rapid diagnostic test for vibrio cholerae o1 during a cholera outbreak in malawi, 2018
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7676503/
https://www.ncbi.nlm.nih.gov/pubmed/33241067
http://dx.doi.org/10.1093/ofid/ofaa493
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