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Comparative efficacy and safety of injection therapies for knee osteoarthritis: A protocol for systematic review and Bayesian network meta analysis
INTRODUCTION: There are many injection methods for the treatment of knee osteoarthritis, but there is no comprehensive comparison, based on the fixed effect model. METHODS: According to the retrieval strategy, we searched randomized controlled trials (RCTs) randomly from PubMed, the Cochrane Library...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7676524/ https://www.ncbi.nlm.nih.gov/pubmed/33217798 http://dx.doi.org/10.1097/MD.0000000000022943 |
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author | Yu, Ting Yan, ShiFan Chi, ZhenHai Zhu, DaoCheng Cheng, Pan Li, HaiYan Qin, SiYu Zhong, GenPing Ouyang, XiLin Chen, RiXin Jiao, Lin |
author_facet | Yu, Ting Yan, ShiFan Chi, ZhenHai Zhu, DaoCheng Cheng, Pan Li, HaiYan Qin, SiYu Zhong, GenPing Ouyang, XiLin Chen, RiXin Jiao, Lin |
author_sort | Yu, Ting |
collection | PubMed |
description | INTRODUCTION: There are many injection methods for the treatment of knee osteoarthritis, but there is no comprehensive comparison, based on the fixed effect model. METHODS: According to the retrieval strategy, we searched randomized controlled trials (RCTs) randomly from PubMed, the Cochrane Library, Embase, the China National Knowledge Infrastructure (CNKI), Wanfang Database from their inceptions to August 2020, and 2 members of us selected literatures and extracted data independently. Methodological quality was assessed by using the Cochrane bias risk tool, and meta-analysis was performed by using the Stat.14.0. RESULTS: This study will evaluate the effectiveness and safety of different injectable drugs for the treatment of knee osteoarthritis and rank the efficacies of drugs, then to determine the optimal treatment. CONCLUSION: This study will provide evidence for the choice of injection therapy for knee osteoarthritis. INPLASY REGISTRATION NUMBER: INPLASY202080099. |
format | Online Article Text |
id | pubmed-7676524 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-76765242020-11-24 Comparative efficacy and safety of injection therapies for knee osteoarthritis: A protocol for systematic review and Bayesian network meta analysis Yu, Ting Yan, ShiFan Chi, ZhenHai Zhu, DaoCheng Cheng, Pan Li, HaiYan Qin, SiYu Zhong, GenPing Ouyang, XiLin Chen, RiXin Jiao, Lin Medicine (Baltimore) 3800 INTRODUCTION: There are many injection methods for the treatment of knee osteoarthritis, but there is no comprehensive comparison, based on the fixed effect model. METHODS: According to the retrieval strategy, we searched randomized controlled trials (RCTs) randomly from PubMed, the Cochrane Library, Embase, the China National Knowledge Infrastructure (CNKI), Wanfang Database from their inceptions to August 2020, and 2 members of us selected literatures and extracted data independently. Methodological quality was assessed by using the Cochrane bias risk tool, and meta-analysis was performed by using the Stat.14.0. RESULTS: This study will evaluate the effectiveness and safety of different injectable drugs for the treatment of knee osteoarthritis and rank the efficacies of drugs, then to determine the optimal treatment. CONCLUSION: This study will provide evidence for the choice of injection therapy for knee osteoarthritis. INPLASY REGISTRATION NUMBER: INPLASY202080099. Lippincott Williams & Wilkins 2020-11-20 /pmc/articles/PMC7676524/ /pubmed/33217798 http://dx.doi.org/10.1097/MD.0000000000022943 Text en Copyright © 2020 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 |
spellingShingle | 3800 Yu, Ting Yan, ShiFan Chi, ZhenHai Zhu, DaoCheng Cheng, Pan Li, HaiYan Qin, SiYu Zhong, GenPing Ouyang, XiLin Chen, RiXin Jiao, Lin Comparative efficacy and safety of injection therapies for knee osteoarthritis: A protocol for systematic review and Bayesian network meta analysis |
title | Comparative efficacy and safety of injection therapies for knee osteoarthritis: A protocol for systematic review and Bayesian network meta analysis |
title_full | Comparative efficacy and safety of injection therapies for knee osteoarthritis: A protocol for systematic review and Bayesian network meta analysis |
title_fullStr | Comparative efficacy and safety of injection therapies for knee osteoarthritis: A protocol for systematic review and Bayesian network meta analysis |
title_full_unstemmed | Comparative efficacy and safety of injection therapies for knee osteoarthritis: A protocol for systematic review and Bayesian network meta analysis |
title_short | Comparative efficacy and safety of injection therapies for knee osteoarthritis: A protocol for systematic review and Bayesian network meta analysis |
title_sort | comparative efficacy and safety of injection therapies for knee osteoarthritis: a protocol for systematic review and bayesian network meta analysis |
topic | 3800 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7676524/ https://www.ncbi.nlm.nih.gov/pubmed/33217798 http://dx.doi.org/10.1097/MD.0000000000022943 |
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