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Childhood adversity and self-poisoning: A hospital case control study in Sri Lanka
INTRODUCTION: Adverse childhood experiences (ACE) have been recognized as an important risk factor for suicidal behaviour among adults, but evidence from low and middle-income countries is lacking. This study explored associations between ACE and hospital admission due to non-fatal self-poisoning in...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7676676/ https://www.ncbi.nlm.nih.gov/pubmed/33211766 http://dx.doi.org/10.1371/journal.pone.0242437 |
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author | Rajapakse, Thilini Russell, Abigail Emma Kidger, Judi Bandara, Piumee López-López, José A. Senarathna, Lalith Metcalfe, Chris Gunnell, David Knipe, Duleeka |
author_facet | Rajapakse, Thilini Russell, Abigail Emma Kidger, Judi Bandara, Piumee López-López, José A. Senarathna, Lalith Metcalfe, Chris Gunnell, David Knipe, Duleeka |
author_sort | Rajapakse, Thilini |
collection | PubMed |
description | INTRODUCTION: Adverse childhood experiences (ACE) have been recognized as an important risk factor for suicidal behaviour among adults, but evidence from low and middle-income countries is lacking. This study explored associations between ACE and hospital admission due to non-fatal self-poisoning in Sri Lanka. METHODS: This was a case-control study. Adults admitted to a tertiary care hospital for medical management of self-poisoning were included as cases, and age and sex matched controls were recruited from the outpatient department. ACE were measured using the World Health Organization’s Childhood Adversity Scale. Logistic regression models adjusting for age, sex, ethnicity, and religion were used to quantify the association between ACE and self-poisoning. RESULTS: The study included 235 cases and 451 controls. Cases were 2.5 times (95% CI 1.8, 3.6) more likely to report an ACE than controls and had higher ACE scores. Childhood physical abuse (OR 4.7, 95% CI 1.2, 19.0) and emotional abuse or neglect (OR 3.7, 95% CI 1.3, 10.1, and 3.7, 95% CI 2.3, 6.0 respectively), increased the risk of self-poisoning in adulthood, as did witnessing household violence (OR 2.2, 95% CI 1.4, 3.4), growing up in a household with a mentally ill or suicidal household member (OR 2.1, 95% CI 1.2, 3.4), and experiencing parental death/separation/divorce (OR 3.1, 95% CI 2.0, 4.9) as a child. CONCLUSIONS: Reducing exposures to ACEs should be a priority for prevention of suicide and self-harm in Sri Lanka. Innovative methods to increase support for children facing adversity should be explored. |
format | Online Article Text |
id | pubmed-7676676 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-76766762020-12-02 Childhood adversity and self-poisoning: A hospital case control study in Sri Lanka Rajapakse, Thilini Russell, Abigail Emma Kidger, Judi Bandara, Piumee López-López, José A. Senarathna, Lalith Metcalfe, Chris Gunnell, David Knipe, Duleeka PLoS One Research Article INTRODUCTION: Adverse childhood experiences (ACE) have been recognized as an important risk factor for suicidal behaviour among adults, but evidence from low and middle-income countries is lacking. This study explored associations between ACE and hospital admission due to non-fatal self-poisoning in Sri Lanka. METHODS: This was a case-control study. Adults admitted to a tertiary care hospital for medical management of self-poisoning were included as cases, and age and sex matched controls were recruited from the outpatient department. ACE were measured using the World Health Organization’s Childhood Adversity Scale. Logistic regression models adjusting for age, sex, ethnicity, and religion were used to quantify the association between ACE and self-poisoning. RESULTS: The study included 235 cases and 451 controls. Cases were 2.5 times (95% CI 1.8, 3.6) more likely to report an ACE than controls and had higher ACE scores. Childhood physical abuse (OR 4.7, 95% CI 1.2, 19.0) and emotional abuse or neglect (OR 3.7, 95% CI 1.3, 10.1, and 3.7, 95% CI 2.3, 6.0 respectively), increased the risk of self-poisoning in adulthood, as did witnessing household violence (OR 2.2, 95% CI 1.4, 3.4), growing up in a household with a mentally ill or suicidal household member (OR 2.1, 95% CI 1.2, 3.4), and experiencing parental death/separation/divorce (OR 3.1, 95% CI 2.0, 4.9) as a child. CONCLUSIONS: Reducing exposures to ACEs should be a priority for prevention of suicide and self-harm in Sri Lanka. Innovative methods to increase support for children facing adversity should be explored. Public Library of Science 2020-11-19 /pmc/articles/PMC7676676/ /pubmed/33211766 http://dx.doi.org/10.1371/journal.pone.0242437 Text en © 2020 Rajapakse et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Rajapakse, Thilini Russell, Abigail Emma Kidger, Judi Bandara, Piumee López-López, José A. Senarathna, Lalith Metcalfe, Chris Gunnell, David Knipe, Duleeka Childhood adversity and self-poisoning: A hospital case control study in Sri Lanka |
title | Childhood adversity and self-poisoning: A hospital case control study in Sri Lanka |
title_full | Childhood adversity and self-poisoning: A hospital case control study in Sri Lanka |
title_fullStr | Childhood adversity and self-poisoning: A hospital case control study in Sri Lanka |
title_full_unstemmed | Childhood adversity and self-poisoning: A hospital case control study in Sri Lanka |
title_short | Childhood adversity and self-poisoning: A hospital case control study in Sri Lanka |
title_sort | childhood adversity and self-poisoning: a hospital case control study in sri lanka |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7676676/ https://www.ncbi.nlm.nih.gov/pubmed/33211766 http://dx.doi.org/10.1371/journal.pone.0242437 |
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