Gender difference in development of steatohepatitis in p62/Sqstm1 and Nrf2 double-knockout mice

Gender and menopause influence the severity and development manner of nonalcoholic steatohepatitis (NASH). Male p62/Sqstm1 and nuclear factor E2-related factor-2 (p62 and Nrf2) double-knockout (DKO) mice exhibit severe steatohepatitis caused by hyperphagia-induced obesity, overload of lipopolysaccha...

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Detalles Bibliográficos
Autores principales: Watahiki, Takahisa, Okada, Kosuke, Warabi, Eiji, Nagaoka, Tsugumi, Suzuki, Hideo, Ishige, Kazunori, Yanagawa, Toru, Takahashi, Satoru, Mizokami, Yuji, Tokushige, Katsutoshi, Ariizumi, Shun-ichi, Yamamoto, Masakazu, Shoda, Junichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2020
Materias:
Original
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677087/
https://www.ncbi.nlm.nih.gov/pubmed/32493884
http://dx.doi.org/10.1538/expanim.20-0028

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