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Functional Peroxisomes Are Essential for Efficient Cholesterol Sensing and Synthesis

Cholesterol biosynthesis is a multi-step process involving several subcellular compartments, including peroxisomes. Cells adjust their sterol content by both transcriptional and post-transcriptional feedback regulation, for which sterol regulatory element-binding proteins (SREBPs) are essential; suc...

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Detalles Bibliográficos
Autores principales: Charles, Khanichi N., Shackelford, Janis E., Faust, Phyllis L., Fliesler, Steven J., Stangl, Herbert, Kovacs, Werner J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677142/
https://www.ncbi.nlm.nih.gov/pubmed/33240873
http://dx.doi.org/10.3389/fcell.2020.560266