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Rescuing ESAT-6 Specific CD4 T Cells From Terminal Differentiation Is Critical for Long-Term Control of Murine Mtb Infection

In most cases, Mycobacterium tuberculosis (Mtb) causes life-long chronic infections, which poses unique challenges for the immune system. Most of the current tuberculosis (TB) subunit vaccines incorporate immunodominant antigens and at this point, it is poorly understood how the CD4 T cell subsets r...

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Detalles Bibliográficos
Autores principales:	Clemmensen, Helena Strand, Knudsen, Niels Peter Hell, Billeskov, Rolf, Rosenkrands, Ida, Jungersen, Gregers, Aagaard, Claus, Andersen, Peter, Mortensen, Rasmus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677256/ https://www.ncbi.nlm.nih.gov/pubmed/33240275 http://dx.doi.org/10.3389/fimmu.2020.585359

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