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Ex vivo rectal explant model reveals potential opposing roles of Natural Killer cells and Marginal Zone-like B cells in HIV-1 infection

Our understanding of innate immune responses in human rectal mucosal tissues (RM) and their contributions to promoting or restricting HIV transmission is limited. We defined the RM composition of innate and innate-like cell subsets, including plasmacytoid dendritic cells; CD1c + myeloid DCs; neutrop...

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Detalles Bibliográficos
Autores principales: Smith, S. Abigail, Murray, Phillip M., Amancha, Praveen Kumar, Ackerley, Cassie G., Hu, Yi-Juan, Amara, Rama R., Kelley, Colleen F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677325/
https://www.ncbi.nlm.nih.gov/pubmed/33214610
http://dx.doi.org/10.1038/s41598-020-76976-5