Functional screening identifies aryl hydrocarbon receptor as suppressor of lung cancer metastasis

Lung cancer mortality largely results from metastasis. Despite curative surgery many patients with early-stage non-small cell lung cancer ultimately succumb to metastatic relapse. Current risk reduction strategies based on cytotoxic chemotherapy and radiation have only modest activity. Against this...

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Detalles Bibliográficos
Autores principales: Nothdurft, Silke, Thumser-Henner, Clotilde, Breitenbücher, Frank, Okimoto, Ross A., Dorsch, Madeleine, Opitz, Christiane A., Sadik, Ahmed, Esser, Charlotte, Hölzel, Michael, Asthana, Saurabh, Forster, Jan, Beisser, Daniela, Kalmbach, Sophie, Grüner, Barbara M., Bivona, Trever G., Schramm, Alexander, Schuler, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677369/
https://www.ncbi.nlm.nih.gov/pubmed/33214553
http://dx.doi.org/10.1038/s41389-020-00286-8

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