Sleep-wake cycles are disrupted by diseases that result in cytoplasmic crowding

It doesn’t take much to disrupt our sleep. Whilst we are aware of environmental factors that can disturb our circadian rhythms, the precise mechanisms that control molecular time cues have remained elusive. Beesley and co-workers demonstrate that diseases associated with cytoplasmic crowding affect...

Descripción completa

Detalles Bibliográficos
Autor principal: Montague-Cardoso, Karli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Research Highlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677373/
https://www.ncbi.nlm.nih.gov/pubmed/33214685
http://dx.doi.org/10.1038/s42003-020-01445-8
_version_ 1783611958485843968
author Montague-Cardoso, Karli
author_facet Montague-Cardoso, Karli
author_sort Montague-Cardoso, Karli
collection PubMed
description It doesn’t take much to disrupt our sleep. Whilst we are aware of environmental factors that can disturb our circadian rhythms, the precise mechanisms that control molecular time cues have remained elusive. Beesley and co-workers demonstrate that diseases associated with cytoplasmic crowding affect the sleep-wake cycle. They also pinpoint a precise time-limiting step in the trafficking of the pacemaker protein PERIOD.
format Online
Article
Text
id pubmed-7677373
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-76773732020-11-20 Sleep-wake cycles are disrupted by diseases that result in cytoplasmic crowding Montague-Cardoso, Karli Commun Biol Research Highlight It doesn’t take much to disrupt our sleep. Whilst we are aware of environmental factors that can disturb our circadian rhythms, the precise mechanisms that control molecular time cues have remained elusive. Beesley and co-workers demonstrate that diseases associated with cytoplasmic crowding affect the sleep-wake cycle. They also pinpoint a precise time-limiting step in the trafficking of the pacemaker protein PERIOD. Nature Publishing Group UK 2020-11-19 /pmc/articles/PMC7677373/ /pubmed/33214685 http://dx.doi.org/10.1038/s42003-020-01445-8 Text en © Springer Nature Limited 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Highlight
Montague-Cardoso, Karli
Sleep-wake cycles are disrupted by diseases that result in cytoplasmic crowding
title Sleep-wake cycles are disrupted by diseases that result in cytoplasmic crowding
title_full Sleep-wake cycles are disrupted by diseases that result in cytoplasmic crowding
title_fullStr Sleep-wake cycles are disrupted by diseases that result in cytoplasmic crowding
title_full_unstemmed Sleep-wake cycles are disrupted by diseases that result in cytoplasmic crowding
title_short Sleep-wake cycles are disrupted by diseases that result in cytoplasmic crowding
title_sort sleep-wake cycles are disrupted by diseases that result in cytoplasmic crowding
topic Research Highlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677373/
https://www.ncbi.nlm.nih.gov/pubmed/33214685
http://dx.doi.org/10.1038/s42003-020-01445-8
work_keys_str_mv AT montaguecardosokarli sleepwakecyclesaredisruptedbydiseasesthatresultincytoplasmiccrowding

Ejemplares similares