Neutrophil serine protease 4 is required for mast cell-dependent vascular leakage

Vascular leakage, or edema, is a serious complication of acute allergic reactions. Vascular leakage is triggered by the release of histamine and serotonin from granules within tissue-resident mast cells. Here, we show that expression of Neutrophil Serine Protease 4 (NSP4) during the early stages of...

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Detalles Bibliográficos
Autores principales: AhYoung, Andrew P., Eckard, Sterling C., Gogineni, Alvin, Xi, Hongkang, Lin, S. Jack, Gerhardy, Stefan, Cox, Christian, Phung, Qui T., Hackney, Jason A., Katakam, Anand Kumar, Reichelt, Mike, Caplazi, Patrick, Manzanillo, Paolo, Zhang, Juan, Roose-Girma, Merone, Tam, Lucinda W., Newman, Robert J., Murthy, Aditya, Weimer, Robby M., Lill, Jennie R., Lee, Wyne P., Grimbaldeston, Michele, Kirchhofer, Daniel, Campagne, Menno van Lookeren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677402/
https://www.ncbi.nlm.nih.gov/pubmed/33214666
http://dx.doi.org/10.1038/s42003-020-01407-0

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