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Lapatinib Plus Local Radiation Therapy for Brain Metastases From HER-2 Positive Breast Cancer Patients and Role of Trastuzumab: A Systematic Review and Meta-Analysis

BACKGROUND: Intracranial activity of lapatinib has been demonstrated in several studies in patients with human epidermal growth factor receptor-2 positive breast cancers (HER-2+ BC). Stereotactic radiosurgery (SRS) has been increasingly used as the local therapy for brain metastases in breast cancer...

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Detalles Bibliográficos
Autores principales: Khan, Muhammad, Zhao, Zhihong, Arooj, Sumbal, Zheng, Tao, Liao, Guixiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677410/
https://www.ncbi.nlm.nih.gov/pubmed/33240815
http://dx.doi.org/10.3389/fonc.2020.576926