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Lung-targeting lentiviral vector for passive immunisation against influenza

When recombinant simian immunodeficiency virus (SIV) is pseudotyped with the F and HN glycoproteins from murine respiratory Sendai virus (rSIV.F/HN), it provides efficient lung cell targeting and lifelong transgene expression in the murine airways. We have shown that a single dose of rSIV.F/HN can d...

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Detalles Bibliográficos
Autores principales: Tan, Tiong Kit, Gamlen, Toby P E, Rijal, Pramila, Townsend, Alain R, Gill, Deborah R, Hyde, Stephen C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677466/
https://www.ncbi.nlm.nih.gov/pubmed/32883885
http://dx.doi.org/10.1136/thoraxjnl-2020-214656