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Untargeted metabolomics yields insight into ALS disease mechanisms

OBJECTIVE: To identify dysregulated metabolic pathways in amyotrophic lateral sclerosis (ALS) versus control participants through untargeted metabolomics. METHODS: Untargeted metabolomics was performed on plasma from ALS participants (n=125) around 6.8 months after diagnosis and healthy controls (n=...

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Detalles Bibliográficos
Autores principales:	Goutman, Stephen A, Boss, Jonathan, Guo, Kai, Alakwaa, Fadhl M, Patterson, Adam, Kim, Sehee, Savelieff, Masha Georges, Hur, Junguk, Feldman, Eva L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2020
Materias:	Neuromuscular
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677469/ https://www.ncbi.nlm.nih.gov/pubmed/32928939 http://dx.doi.org/10.1136/jnnp-2020-323611

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