Unique expansion of IL-21+ Tfh and Tph cells under control of ICOS identifies Sjögren’s syndrome with ectopic germinal centres and MALT lymphoma

OBJECTIVES: To explore the relevance of T-follicular-helper (Tfh) and pathogenic peripheral-helper T-cells (Tph) in promoting ectopic lymphoid structures (ELS) and B-cell mucosa-associated lymphoid tissue (MALT) lymphomas (MALT-L) in Sjögren’s syndrome (SS) patients. METHODS: Salivary gland (SG) bio...

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Detalles Bibliográficos
Autores principales: Pontarini, Elena, Murray-Brown, William James, Croia, Cristina, Lucchesi, Davide, Conway, James, Rivellese, Felice, Fossati-Jimack, Liliane, Astorri, Elisa, Prediletto, Edoardo, Corsiero, Elisa, Romana Delvecchio, Francesca, Coleby, Rachel, Gelbhardt, Eva, Bono, Aurora, Baldini, Chiara, Puxeddu, Ilaria, Ruscitti, Piero, Giacomelli, Roberto, Barone, Francesca, Fisher, Benjamin, Bowman, Simon J, Colafrancesco, Serena, Priori, Roberta, Sutcliffe, Nurhan, Challacombe, Stephen, Carlesso, Gianluca, Tappuni, Anwar, Pitzalis, Costantino, Bombardieri, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Sjögren's Syndrome
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677495/
https://www.ncbi.nlm.nih.gov/pubmed/32963045
http://dx.doi.org/10.1136/annrheumdis-2020-217646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677495/
https://www.ncbi.nlm.nih.gov/pubmed/32963045
http://dx.doi.org/10.1136/annrheumdis-2020-217646

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