Identification of Novel BRCA1 and RAD50 Mutations Associated With Breast Cancer Predisposition in Tunisian Patients

BACKGROUND: Deleterious mutations on BRCA1/2 genes are known to confer high risk of developing breast and ovarian cancers. The identification of these mutations not only helped in selecting high risk individuals that need appropriate prevention approaches but also led to the development of the PARP-...

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Detalles Bibliográficos
Autores principales: Mighri, Najah, Hamdi, Yosr, Boujemaa, Maroua, Othman, Houcemeddine, Ben Nasr, Sonia, El Benna, Houda, Mejri, Nesrine, Labidi, Soumaya, Ayari, Jihen, Jaidene, Olfa, Bouaziz, Hanen, Ben Rekaya, Mariem, M’rad, Ridha, Haddaoui, Abderrazek, Rahal, Khaled, Boussen, Hamouda, Boubaker, Samir, Abdelhak, Sonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677579/
https://www.ncbi.nlm.nih.gov/pubmed/33240314
http://dx.doi.org/10.3389/fgene.2020.552971

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