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Application of zebrafish to safety evaluation in drug discovery

Traditionally, safety evaluation at the early stage of drug discovery research has been done using in silico, in vitro, and in vivo systems in this order because of limitations on the amount of compounds available and the throughput ability of the assay systems. While these in vitro assays are very...

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Detalles Bibliográficos
Autor principal: Miyawaki, Izuru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677624/
https://www.ncbi.nlm.nih.gov/pubmed/33239838
http://dx.doi.org/10.1293/tox.2020-0021

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