Primary malignant melanoma of the female urethra: A case report

Primary malignant melanoma of a female urethra is extremely rare. A 71-year-old female was referred to our hospital with bleeding from the urethral meatus. Magnetic resonance imaging revealed a mass of 25 mm in diameter at the external urethral meatus. She underwent anterior pelvic exenteration and...

Descripción completa

Detalles Bibliográficos
Autores principales: Watanabe, Kazuhiro, Hasegawa, Go, Kashima, Katsunori, Sato, Yo, Hara, Noboru, Nishiyama, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677670/
https://www.ncbi.nlm.nih.gov/pubmed/33251115
http://dx.doi.org/10.1016/j.eucr.2020.101493
_version_ 1783612021869117440
author Watanabe, Kazuhiro
Hasegawa, Go
Kashima, Katsunori
Sato, Yo
Hara, Noboru
Nishiyama, Tsutomu
author_facet Watanabe, Kazuhiro
Hasegawa, Go
Kashima, Katsunori
Sato, Yo
Hara, Noboru
Nishiyama, Tsutomu
author_sort Watanabe, Kazuhiro
collection PubMed
description Primary malignant melanoma of a female urethra is extremely rare. A 71-year-old female was referred to our hospital with bleeding from the urethral meatus. Magnetic resonance imaging revealed a mass of 25 mm in diameter at the external urethral meatus. She underwent anterior pelvic exenteration and ileal conduit diversion. Histopathological findings were urethral malignant melanoma, pT3apN0M0 (stage IIA). Nine months after surgery, computed tomography revealed a local recurrence in the pelvis, the patient was treated with immunotherapy using combined nivolumab and ipilimumab; however, she did not respond to treatment and died 22 months following diagnosis.
format Online
Article
Text
id pubmed-7677670
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-76776702020-11-27 Primary malignant melanoma of the female urethra: A case report Watanabe, Kazuhiro Hasegawa, Go Kashima, Katsunori Sato, Yo Hara, Noboru Nishiyama, Tsutomu Urol Case Rep Oncology Primary malignant melanoma of a female urethra is extremely rare. A 71-year-old female was referred to our hospital with bleeding from the urethral meatus. Magnetic resonance imaging revealed a mass of 25 mm in diameter at the external urethral meatus. She underwent anterior pelvic exenteration and ileal conduit diversion. Histopathological findings were urethral malignant melanoma, pT3apN0M0 (stage IIA). Nine months after surgery, computed tomography revealed a local recurrence in the pelvis, the patient was treated with immunotherapy using combined nivolumab and ipilimumab; however, she did not respond to treatment and died 22 months following diagnosis. Elsevier 2020-11-12 /pmc/articles/PMC7677670/ /pubmed/33251115 http://dx.doi.org/10.1016/j.eucr.2020.101493 Text en © 2020 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Oncology
Watanabe, Kazuhiro
Hasegawa, Go
Kashima, Katsunori
Sato, Yo
Hara, Noboru
Nishiyama, Tsutomu
Primary malignant melanoma of the female urethra: A case report
title Primary malignant melanoma of the female urethra: A case report
title_full Primary malignant melanoma of the female urethra: A case report
title_fullStr Primary malignant melanoma of the female urethra: A case report
title_full_unstemmed Primary malignant melanoma of the female urethra: A case report
title_short Primary malignant melanoma of the female urethra: A case report
title_sort primary malignant melanoma of the female urethra: a case report
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677670/
https://www.ncbi.nlm.nih.gov/pubmed/33251115
http://dx.doi.org/10.1016/j.eucr.2020.101493
work_keys_str_mv AT watanabekazuhiro primarymalignantmelanomaofthefemaleurethraacasereport
AT hasegawago primarymalignantmelanomaofthefemaleurethraacasereport
AT kashimakatsunori primarymalignantmelanomaofthefemaleurethraacasereport
AT satoyo primarymalignantmelanomaofthefemaleurethraacasereport
AT haranoboru primarymalignantmelanomaofthefemaleurethraacasereport
AT nishiyamatsutomu primarymalignantmelanomaofthefemaleurethraacasereport

Ejemplares similares