Adding flexibility to clinical trial designs: an example-based guide to the practical use of adaptive designs

Adaptive designs for clinical trials permit alterations to a study in response to accumulating data in order to make trials more flexible, ethical, and efficient. These benefits are achieved while preserving the integrity and validity of the trial, through the pre-specification and proper adjustment...

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Detalles Bibliográficos
Autores principales: Burnett, Thomas, Mozgunov, Pavel, Pallmann, Philip, Villar, Sofia S., Wheeler, Graham M., Jaki, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677786/
https://www.ncbi.nlm.nih.gov/pubmed/33208155
http://dx.doi.org/10.1186/s12916-020-01808-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677786/
https://www.ncbi.nlm.nih.gov/pubmed/33208155
http://dx.doi.org/10.1186/s12916-020-01808-2

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