Deep sequencing reveals a DAP1 regulatory haplotype that potentiates autoimmunity in systemic lupus erythematosus

BACKGROUND: Systemic lupus erythematosus (SLE) is a clinically heterogeneous autoimmune disease characterized by the development of anti-nuclear antibodies. Susceptibility to SLE is multifactorial, with a combination of genetic and environmental risk factors contributing to disease development. Like...

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Detalles Bibliográficos
Autores principales: Raj, Prithvi, Song, Ran, Zhu, Honglin, Riediger, Linley, Jun, Dong-Jae, Liang, Chaoying, Arana, Carlos, Zhang, Bo, Gao, Yajing, Wakeland, Benjamin E., Dozmorov, Igor, Zhou, Jinchun, Kelly, Jennifer A., Lauwerys, Bernard R., Guthridge, Joel M., Olsen, Nancy J., Nath, Swapan K., Pasare, Chandrashekhar, van Oers, Nicolai, Gilkeson, Gary, Tsao, Betty P., Gaffney, Patrick M., Gregersen, Peter K., James, Judith A., Zuo, Xiaoxia, Karp, David R., Li, Quan-Zhen, Wakeland, Edward K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677828/
https://www.ncbi.nlm.nih.gov/pubmed/33213505
http://dx.doi.org/10.1186/s13059-020-02184-z

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