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Crosstalk between microglia and patient-derived glioblastoma cells inhibit invasion in a three-dimensional gelatin hydrogel model
BACKGROUND: Glioblastoma is the most common and deadly form of primary brain cancer, accounting for more than 13,000 new diagnoses annually in the USA alone. Microglia are the innate immune cells within the central nervous system, acting as a front-line defense against injuries and inflammation via...
Autores principales: | Chen, Jee-Wei Emily, Lumibao, Jan, Leary, Sarah, Sarkaria, Jann N., Steelman, Andrew J., Gaskins, H. Rex, Harley, Brendan A. C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677841/ https://www.ncbi.nlm.nih.gov/pubmed/33208156 http://dx.doi.org/10.1186/s12974-020-02026-6 |
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