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Bivalent genes that undergo transcriptional switching identify networks of key regulators of embryonic stem cell differentiation

BACKGROUND: Bivalent promoters marked with both H3K27me3 and H3K4me3 histone modifications are characteristic of poised promoters in embryonic stem (ES) cells. The model of poised promoters postulates that bivalent chromatin in ES cells is resolved to monovalency upon differntiation. With the availa...

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Detalles Bibliográficos
Autores principales:	Jeon, Ah-Jung, Tucker-Kellogg, Greg
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677846/ https://www.ncbi.nlm.nih.gov/pubmed/33208095 http://dx.doi.org/10.1186/s12864-020-07009-8

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