Emergence of carbapenem-resistant ST131 Escherichia coli carrying bla (OXA-244) in Germany, 2019 to 2020

The dissemination of carbapenem-producing Gram-negative bacteria is a major public health concern. We report the first detection of OXA-244-producing ST131 O16:H5 Escherichia coli in three patients from two tertiary hospitals in the south-west of Germany. OXA-244 is emerging in Europe. Because of de...

Descripción completa

Detalles Bibliográficos
Autores principales: Welker, Sybille, Boutin, Sébastien, Miethke, Thomas, Heeg, Klaus, Nurjadi, Dennis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2020
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678038/
https://www.ncbi.nlm.nih.gov/pubmed/33213685
http://dx.doi.org/10.2807/1560-7917.ES.2020.25.46.2001815
Descripción
Sumario:The dissemination of carbapenem-producing Gram-negative bacteria is a major public health concern. We report the first detection of OXA-244-producing ST131 O16:H5 Escherichia coli in three patients from two tertiary hospitals in the south-west of Germany. OXA-244 is emerging in Europe. Because of detection challenges, OXA-244-producing E. coli may be under-reported. The emergence of carbapenem resistance in a globally circulating high-risk clone, such as ST131 E. coli is of clinical relevance and should be monitored closely.

Ejemplares similares