Emergence of carbapenem-resistant ST131 Escherichia coli carrying bla (OXA-244) in Germany, 2019 to 2020

The dissemination of carbapenem-producing Gram-negative bacteria is a major public health concern. We report the first detection of OXA-244-producing ST131 O16:H5 Escherichia coli in three patients from two tertiary hospitals in the south-west of Germany. OXA-244 is emerging in Europe. Because of de...

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Autores principales: Welker, Sybille, Boutin, Sébastien, Miethke, Thomas, Heeg, Klaus, Nurjadi, Dennis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2020
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678038/
https://www.ncbi.nlm.nih.gov/pubmed/33213685
http://dx.doi.org/10.2807/1560-7917.ES.2020.25.46.2001815
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author Welker, Sybille
Boutin, Sébastien
Miethke, Thomas
Heeg, Klaus
Nurjadi, Dennis
author_facet Welker, Sybille
Boutin, Sébastien
Miethke, Thomas
Heeg, Klaus
Nurjadi, Dennis
author_sort Welker, Sybille
collection PubMed
description The dissemination of carbapenem-producing Gram-negative bacteria is a major public health concern. We report the first detection of OXA-244-producing ST131 O16:H5 Escherichia coli in three patients from two tertiary hospitals in the south-west of Germany. OXA-244 is emerging in Europe. Because of detection challenges, OXA-244-producing E. coli may be under-reported. The emergence of carbapenem resistance in a globally circulating high-risk clone, such as ST131 E. coli is of clinical relevance and should be monitored closely.
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spelling pubmed-76780382020-11-23 Emergence of carbapenem-resistant ST131 Escherichia coli carrying bla (OXA-244) in Germany, 2019 to 2020 Welker, Sybille Boutin, Sébastien Miethke, Thomas Heeg, Klaus Nurjadi, Dennis Euro Surveill Rapid Communication The dissemination of carbapenem-producing Gram-negative bacteria is a major public health concern. We report the first detection of OXA-244-producing ST131 O16:H5 Escherichia coli in three patients from two tertiary hospitals in the south-west of Germany. OXA-244 is emerging in Europe. Because of detection challenges, OXA-244-producing E. coli may be under-reported. The emergence of carbapenem resistance in a globally circulating high-risk clone, such as ST131 E. coli is of clinical relevance and should be monitored closely. European Centre for Disease Prevention and Control (ECDC) 2020-11-19 /pmc/articles/PMC7678038/ /pubmed/33213685 http://dx.doi.org/10.2807/1560-7917.ES.2020.25.46.2001815 Text en This article is copyright of the authors or their affiliated institutions, 2020. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.
spellingShingle Rapid Communication
Welker, Sybille
Boutin, Sébastien
Miethke, Thomas
Heeg, Klaus
Nurjadi, Dennis
Emergence of carbapenem-resistant ST131 Escherichia coli carrying bla (OXA-244) in Germany, 2019 to 2020
title Emergence of carbapenem-resistant ST131 Escherichia coli carrying bla (OXA-244) in Germany, 2019 to 2020
title_full Emergence of carbapenem-resistant ST131 Escherichia coli carrying bla (OXA-244) in Germany, 2019 to 2020
title_fullStr Emergence of carbapenem-resistant ST131 Escherichia coli carrying bla (OXA-244) in Germany, 2019 to 2020
title_full_unstemmed Emergence of carbapenem-resistant ST131 Escherichia coli carrying bla (OXA-244) in Germany, 2019 to 2020
title_short Emergence of carbapenem-resistant ST131 Escherichia coli carrying bla (OXA-244) in Germany, 2019 to 2020
title_sort emergence of carbapenem-resistant st131 escherichia coli carrying bla (oxa-244) in germany, 2019 to 2020
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678038/
https://www.ncbi.nlm.nih.gov/pubmed/33213685
http://dx.doi.org/10.2807/1560-7917.ES.2020.25.46.2001815
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