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The safety of Ramadan Fasting following Percutaneous Coronary Intervention

BACKGROUND: This work aimed to assess the safety of Ramadan Fasting following the Percutaneous Coronary Intervention. METHODS: In our two centers’ Prospective Cohort Study, We included 303 patients who had successful Percutaneous Coronary Intervention before the first day of Ramadan. We advised the...

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Autores principales: Amin, Osama A., Alaarag, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678075/
https://www.ncbi.nlm.nih.gov/pubmed/33213367
http://dx.doi.org/10.1186/s12872-020-01784-8
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author Amin, Osama A.
Alaarag, Ahmed
author_facet Amin, Osama A.
Alaarag, Ahmed
author_sort Amin, Osama A.
collection PubMed
description BACKGROUND: This work aimed to assess the safety of Ramadan Fasting following the Percutaneous Coronary Intervention. METHODS: In our two centers’ Prospective Cohort Study, We included 303 patients who had successful Percutaneous Coronary Intervention before the first day of Ramadan. We advised the patients that recent Percutaneous Coronary Intervention could be a valid excuse for not fulfilling Ramadan Fasting. However, many patients intended to fast the following Ramadan, and we included them in the fasting Group I. We added the patients who decided not to fast the following Ramadan as a control Group II. We followed all the patients during Ramadan and for 6 months after Ramadan. RESULTS: The demographic data of both groups and the complexity of the coronary anatomy showed no statistically significant difference. Group I (n = 153) showed a statistically significant difference in the incidence of Major Adverse Cardiac Events compared to Group II with a P value (0.005). The logistic multivariate regression analysis showed that the duration from index PCI till the start of RF, SYNTAX score > 22, and Complex procedure were independent predictors of Major Adverse Cardiac Events in the fasting Group I with {P = 0.001, OR (2.302), P = 0.026, OR (2.419), and P = 0.032 OR (1.952)}, respectively. Major Adverse Cardiac Events in Group I occurred mainly during Ramadan Fasting, with 19 patients having Major Adverse Cardiac Events during Ramadan and four patients during the remaining of the follow-up period. The Receiver Operating Characteristic curve analysis showed the decline of the incidence of Major Adverse Cardiac Events after 90 days from Percutaneous Coronary Intervention till the start of Ramadan Fasting with Sensitivity and specificity (90% and 65%), respectively. CONCLUSIONS: We suggest that low-risk patients with a normal systolic function who underwent Percutaneous Coronary Intervention may safely fast Ramadan. At the same time, Ramadan Fasting during the first 3 months following the Percutaneous Coronary Intervention may not be safe.
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spelling pubmed-76780752020-11-20 The safety of Ramadan Fasting following Percutaneous Coronary Intervention Amin, Osama A. Alaarag, Ahmed BMC Cardiovasc Disord Research Article BACKGROUND: This work aimed to assess the safety of Ramadan Fasting following the Percutaneous Coronary Intervention. METHODS: In our two centers’ Prospective Cohort Study, We included 303 patients who had successful Percutaneous Coronary Intervention before the first day of Ramadan. We advised the patients that recent Percutaneous Coronary Intervention could be a valid excuse for not fulfilling Ramadan Fasting. However, many patients intended to fast the following Ramadan, and we included them in the fasting Group I. We added the patients who decided not to fast the following Ramadan as a control Group II. We followed all the patients during Ramadan and for 6 months after Ramadan. RESULTS: The demographic data of both groups and the complexity of the coronary anatomy showed no statistically significant difference. Group I (n = 153) showed a statistically significant difference in the incidence of Major Adverse Cardiac Events compared to Group II with a P value (0.005). The logistic multivariate regression analysis showed that the duration from index PCI till the start of RF, SYNTAX score > 22, and Complex procedure were independent predictors of Major Adverse Cardiac Events in the fasting Group I with {P = 0.001, OR (2.302), P = 0.026, OR (2.419), and P = 0.032 OR (1.952)}, respectively. Major Adverse Cardiac Events in Group I occurred mainly during Ramadan Fasting, with 19 patients having Major Adverse Cardiac Events during Ramadan and four patients during the remaining of the follow-up period. The Receiver Operating Characteristic curve analysis showed the decline of the incidence of Major Adverse Cardiac Events after 90 days from Percutaneous Coronary Intervention till the start of Ramadan Fasting with Sensitivity and specificity (90% and 65%), respectively. CONCLUSIONS: We suggest that low-risk patients with a normal systolic function who underwent Percutaneous Coronary Intervention may safely fast Ramadan. At the same time, Ramadan Fasting during the first 3 months following the Percutaneous Coronary Intervention may not be safe. BioMed Central 2020-11-19 /pmc/articles/PMC7678075/ /pubmed/33213367 http://dx.doi.org/10.1186/s12872-020-01784-8 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Amin, Osama A.
Alaarag, Ahmed
The safety of Ramadan Fasting following Percutaneous Coronary Intervention
title The safety of Ramadan Fasting following Percutaneous Coronary Intervention
title_full The safety of Ramadan Fasting following Percutaneous Coronary Intervention
title_fullStr The safety of Ramadan Fasting following Percutaneous Coronary Intervention
title_full_unstemmed The safety of Ramadan Fasting following Percutaneous Coronary Intervention
title_short The safety of Ramadan Fasting following Percutaneous Coronary Intervention
title_sort safety of ramadan fasting following percutaneous coronary intervention
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678075/
https://www.ncbi.nlm.nih.gov/pubmed/33213367
http://dx.doi.org/10.1186/s12872-020-01784-8
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