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High-fat diet-induced and genetically inherited obesity differentially alters DNA methylation profile in the germline of adult male rats
BACKGROUND: Paternal obesity has been associated with reduced live birth rates. It could lead to inheritance of metabolic disturbances to the offspring through epigenetic mechanisms. However, obesity is a multifactorial disorder with genetic or environmental causes. Earlier we had demonstrated diffe...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678167/ https://www.ncbi.nlm.nih.gov/pubmed/33213487 http://dx.doi.org/10.1186/s13148-020-00974-7 |