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Characterization of an N-terminal Na(v)1.5 channel variant – a potential risk factor for arrhythmias and sudden death?
BACKGROUND: Alterations in the SCN5A gene encoding the cardiac sodium channel Na(v)1.5 have been linked to a number of arrhythmia syndromes and diseases including long-QT syndrome (LQTS), Brugada syndrome (BrS) and dilative cardiomyopathy (DCM), which may predispose to fatal arrhythmias and sudden d...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678220/ https://www.ncbi.nlm.nih.gov/pubmed/33213388 http://dx.doi.org/10.1186/s12881-020-01170-3 |