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Clinical significance of ERBB2 exon 16 skipping: analysis of a real-world retrospective observational cohort study

BACKGROUND: ERBB2 exon 16 skipping is an alternatively spliced isoform of ERBB2, which was reported to lead to oncogenic activation of ERBB2 and could potentially cause tyrosine kinase inhibitor (TKI) resistance in non-small cell lung cancer (NSCLC) in case studies. In this study, we aimed to evalua...

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Detalles Bibliográficos
Autores principales: Shi, Lei, Xu, Caihua, Ma, Yutong, Ou, Qiuxiang, Wu, Xue, Lu, Songhua, Shao, Yang, Guo, Renhua, Kong, Jinliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678393/
https://www.ncbi.nlm.nih.gov/pubmed/33214226
http://dx.doi.org/10.1136/esmoopen-2020-000985