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Patch Test Results of 276 Cases with Footwear Dermatitis - A Retrospective Study from a Tertiary Care Centre in South India

BACKGROUND: Allergic contact dermatitis (ACD) is a major cause for foot wear dermatitis. Patch testing is the standard investigation for diagnosis of ACD. Identification of the causative allergen and avoidance of the same is the most important for patient management. AIMS: This study was conducted t...

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Autores principales: Thyvalappil, Anoop, Sridharan, Rajiv, Amrutha, M. P., Nair, Gayathri, Sreenivasan, Ajayakumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678548/
https://www.ncbi.nlm.nih.gov/pubmed/33235836
http://dx.doi.org/10.4103/idoj.IDOJ_560_19
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author Thyvalappil, Anoop
Sridharan, Rajiv
Amrutha, M. P.
Nair, Gayathri
Sreenivasan, Ajayakumar
author_facet Thyvalappil, Anoop
Sridharan, Rajiv
Amrutha, M. P.
Nair, Gayathri
Sreenivasan, Ajayakumar
author_sort Thyvalappil, Anoop
collection PubMed
description BACKGROUND: Allergic contact dermatitis (ACD) is a major cause for foot wear dermatitis. Patch testing is the standard investigation for diagnosis of ACD. Identification of the causative allergen and avoidance of the same is the most important for patient management. AIMS: This study was conducted to find the common allergens in footwear, causing ACD, by retrospective analysis of the data of patients who had undergone patch testing with footwear series (FWS), approved by the Contact and Occupational Dermatoses Forum of India. MATERIALS AND METHODS: A total of 276 cases with footwear dermatitis who underwent patch test with FWS using Finn chamber method were studied. Statistical analysis was done using statistical package for social sciences (SPSS) version 24. Data was described using frequency and percentages. P value of less than 0.05 was considered significant. RESULTS: In this study 101 (36.5%) patients had positive patch test to at least one allergen. Among this, 43 (15.6%) were positive for single allergen only and 58 (21.01%) patients had positive patch test reactions to multiple allergens. The most common allergens with positive patch test were black rubber mix, mercapto benzo thiazole, and thiuram mix. Patients with either a positive or negative patch test had no statistically significant difference in the history of atopy. The limitations of this study include the lack of patch testing with the patient's own footwears and lack of follow-up after informing patients regarding allergen avoidance. CONCLUSIONS: Patch test must be done for all foot eczema cases for early identification of the causative allergen and also to provide suitable alternatives.
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spelling pubmed-76785482020-11-23 Patch Test Results of 276 Cases with Footwear Dermatitis - A Retrospective Study from a Tertiary Care Centre in South India Thyvalappil, Anoop Sridharan, Rajiv Amrutha, M. P. Nair, Gayathri Sreenivasan, Ajayakumar Indian Dermatol Online J Original Article BACKGROUND: Allergic contact dermatitis (ACD) is a major cause for foot wear dermatitis. Patch testing is the standard investigation for diagnosis of ACD. Identification of the causative allergen and avoidance of the same is the most important for patient management. AIMS: This study was conducted to find the common allergens in footwear, causing ACD, by retrospective analysis of the data of patients who had undergone patch testing with footwear series (FWS), approved by the Contact and Occupational Dermatoses Forum of India. MATERIALS AND METHODS: A total of 276 cases with footwear dermatitis who underwent patch test with FWS using Finn chamber method were studied. Statistical analysis was done using statistical package for social sciences (SPSS) version 24. Data was described using frequency and percentages. P value of less than 0.05 was considered significant. RESULTS: In this study 101 (36.5%) patients had positive patch test to at least one allergen. Among this, 43 (15.6%) were positive for single allergen only and 58 (21.01%) patients had positive patch test reactions to multiple allergens. The most common allergens with positive patch test were black rubber mix, mercapto benzo thiazole, and thiuram mix. Patients with either a positive or negative patch test had no statistically significant difference in the history of atopy. The limitations of this study include the lack of patch testing with the patient's own footwears and lack of follow-up after informing patients regarding allergen avoidance. CONCLUSIONS: Patch test must be done for all foot eczema cases for early identification of the causative allergen and also to provide suitable alternatives. Wolters Kluwer - Medknow 2020-09-19 /pmc/articles/PMC7678548/ /pubmed/33235836 http://dx.doi.org/10.4103/idoj.IDOJ_560_19 Text en Copyright: © 2020 Indian Dermatology Online Journal http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Thyvalappil, Anoop
Sridharan, Rajiv
Amrutha, M. P.
Nair, Gayathri
Sreenivasan, Ajayakumar
Patch Test Results of 276 Cases with Footwear Dermatitis - A Retrospective Study from a Tertiary Care Centre in South India
title Patch Test Results of 276 Cases with Footwear Dermatitis - A Retrospective Study from a Tertiary Care Centre in South India
title_full Patch Test Results of 276 Cases with Footwear Dermatitis - A Retrospective Study from a Tertiary Care Centre in South India
title_fullStr Patch Test Results of 276 Cases with Footwear Dermatitis - A Retrospective Study from a Tertiary Care Centre in South India
title_full_unstemmed Patch Test Results of 276 Cases with Footwear Dermatitis - A Retrospective Study from a Tertiary Care Centre in South India
title_short Patch Test Results of 276 Cases with Footwear Dermatitis - A Retrospective Study from a Tertiary Care Centre in South India
title_sort patch test results of 276 cases with footwear dermatitis - a retrospective study from a tertiary care centre in south india
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678548/
https://www.ncbi.nlm.nih.gov/pubmed/33235836
http://dx.doi.org/10.4103/idoj.IDOJ_560_19
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