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Dexmedetomidine inhibits the PSD95-NMDA receptor interaction to promote functional recovery following traumatic brain injury

The present study examined the effects of dexmedetomidine (Dex) on cognitive and motor recovery in mice following traumatic brain injury (TBI). TBI induces synaptic damage, which leads to motor dysfunction and cognitive decline. Although Dex is known to induce neuroprotection, its role following TBI...

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Detalles Bibliográficos
Autores principales: Zhao, Zhongbai, Ren, Yu, Jiang, Hong, Huang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678629/
https://www.ncbi.nlm.nih.gov/pubmed/33235613
http://dx.doi.org/10.3892/etm.2020.9436