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Cysteine-Altering NOTCH3 Variants Are a Risk Factor for Stroke in the Elderly Population

Cysteine altering NOTCH3 variants, which have previously been exclusively associated with the rare hereditary small vessel disease cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy, have a population frequency of 1:300 worldwide. Using a large population data...

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Detalles Bibliográficos
Autores principales:	Hack, Remco J., Rutten, Julie W., Person, Thomas N., Li, Jiang, Khan, Ayesha, Griessenauer, Christoph J., Abedi, Vida, Lesnik Oberstein, Saskia A.J., Zand, Ramin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2020
Materias:	Original Contributions
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678653/ https://www.ncbi.nlm.nih.gov/pubmed/33161844 http://dx.doi.org/10.1161/STROKEAHA.120.030343

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