Cargando…

Cadmium stress dictates central carbon flux and alters membrane composition in Streptococcus pneumoniae

Metal ion homeostasis is essential for all forms of life. However, the breadth of intracellular impacts that arise upon dysregulation of metal ion homeostasis remain to be elucidated. Here, we used cadmium, a non-physiological metal ion, to investigate how the bacterial pathogen, Streptococcus pneum...

Descripción completa

Detalles Bibliográficos
Autores principales:	Neville, Stephanie L., Eijkelkamp, Bart A., Lothian, Amber, Paton, James C., Roberts, Blaine R., Rosch, Jason W., McDevitt, Christopher A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678824/ https://www.ncbi.nlm.nih.gov/pubmed/33214631 http://dx.doi.org/10.1038/s42003-020-01417-y

Ejemplares similares

Dysregulation of transition metal ion homeostasis is the molecular basis for cadmium toxicity in Streptococcus pneumoniae
por: Begg, Stephanie L., et al.
Publicado: (2015)

Extracellular Zinc Competitively Inhibits Manganese Uptake and Compromises Oxidative Stress Management in Streptococcus pneumoniae
por: Eijkelkamp, Bart A., et al.
Publicado: (2014)

Host-Mediated Copper Stress Is Not Protective against Streptococcus pneumoniae D39 Infection
por: Neville, Stephanie L., et al.
Publicado: (2022)

Dysregulation of Streptococcus pneumoniae zinc homeostasis breaks ampicillin resistance in a pneumonia infection model
por: Brazel, Erin B., et al.
Publicado: (2022)

Dietary zinc and the control of Streptococcus pneumoniae infection
por: Eijkelkamp, Bart A., et al.
Publicado: (2019)

Standards for Quantitative Metalloproteomic Analysis Using Size Exclusion ICP-MS
por: Lothian, Amber, et al.
Publicado: (2016)

The role of CopA in Streptococcus pyogenes copper homeostasis and virulence
por: Dao, Tina H., et al.
Publicado: (2023)

Autoinducer 2 Signaling via the Phosphotransferase FruA Drives Galactose Utilization by Streptococcus pneumoniae, Resulting in Hypervirulence
por: Trappetti, Claudia, et al.
Publicado: (2017)

A Trap-Door Mechanism for Zinc Acquisition by Streptococcus pneumoniae AdcA
por: Luo, Zhenyao, et al.
Publicado: (2021)

Conformation of the Solute-Binding Protein AdcAII Influences Zinc Uptake in Streptococcus pneumoniae
por: Župan, Marina L., et al.
Publicado: (2021)

Central carbon flux controls growth/damage balance for Streptococcus pyogenes
por: Merriman, Joseph A., et al.
Publicado: (2023)

Zinc stress induces copper depletion in Acinetobacter baumannii
por: Hassan, Karl A., et al.
Publicado: (2017)

Epigenetic Switch Driven by DNA Inversions Dictates Phase Variation in Streptococcus pneumoniae
por: Li, Jing, et al.
Publicado: (2016)

ZnuA and zinc homeostasis in Pseudomonas aeruginosa
por: Pederick, Victoria G., et al.
Publicado: (2015)

Arachidonic Acid Stress Impacts Pneumococcal Fatty Acid Homeostasis
por: Eijkelkamp, Bart A., et al.
Publicado: (2018)

Advancing Genetic Tools in Streptococcus pneumoniae
por: Echlin, Haley, et al.
Publicado: (2020)

Hydrogen Peroxide Production by Streptococcus pneumoniae Results in Alpha-hemolysis by Oxidation of Oxy-hemoglobin to Met-hemoglobin
por: McDevitt, Erin, et al.
Publicado: (2020)

The Role of the CopA Copper Efflux System in Acinetobacter baumannii Virulence
por: Alquethamy, Saleh F., et al.
Publicado: (2019)

Differences in genetic flux in invasive Streptococcus pneumoniae associated with bacteraemia and meningitis()
por: Mutua, Teresa M., et al.
Publicado: (2022)

Mechanistic investigation of a D to N mutation in DAHP synthase that dictates carbon flux into the shikimate pathway in yeast
por: Liu, Huayi, et al.
Publicado: (2023)

Metalloproteomics: principles, challenges and applications to neurodegeneration
por: Lothian, Amber, et al.
Publicado: (2013)

An optimal regulation of fluxes dictates microbial growth in and out of steady state
por: Chure, Griffin, et al.
Publicado: (2023)

The roles of transition metals in the physiology and pathogenesis of Streptococcus pneumoniae
por: Honsa, Erin S., et al.
Publicado: (2013)

The central role of arginine in Haemophilus influenzae survival in a polymicrobial environment with Streptococcus pneumoniae and Moraxella catarrhalis
por: Tikhomirova, Alexandra, et al.
Publicado: (2022)

JMM Profile: Streptococcus pneumoniae: sugar-coated captain of the men of death
por: Dao, Tina H., et al.
Publicado: (2021)

The Impact of Pneumolysin on the Macrophage Response to Streptococcus pneumoniae is Strain-Dependent
por: Harvey, Richard M., et al.
Publicado: (2014)

The Role of ZntA in Klebsiella pneumoniae Zinc Homeostasis
por: Maunders, Eve A., et al.
Publicado: (2022)

Control of Virulence by Small RNAs in Streptococcus pneumoniae
por: Mann, Beth, et al.
Publicado: (2012)

Pyruvate oxidase of Streptococcus pneumoniae contributes to pneumolysin release
por: Bryant, Joseph C., et al.
Publicado: (2016)

A Transcription Factor Contributes to Pathogenesis and Virulence in Streptococcus pneumoniae
por: Mahdi, Layla K., et al.
Publicado: (2013)

Comparison of contemporary invasive and non-invasive Streptococcus pneumoniae isolates reveals new insights into circulating anti-microbial resistance determinants
por: Higgs, Charlie, et al.
Publicado: (2023)

Identification of Novel Acinetobacter baumannii Host Fatty Acid Stress Adaptation Strategies
por: Jiang, Jhih-Hang, et al.
Publicado: (2019)

Taurine Alleviates Cadmium-Induced Hepatotoxicity by Regulating Autophagy Flux
por: Duan, Yuntian, et al.
Publicado: (2023)

Assessment of transcriptomic constraint-based methods for central carbon flux inference
por: Bhadra-Lobo, Siddharth, et al.
Publicado: (2020)

Carbon source regulates polysaccharide capsule biosynthesis in Streptococcus pneumoniae
por: Troxler, Lukas J., et al.
Publicado: (2019)

The Role of luxS in the Middle Ear Streptococcus pneumoniae Isolate 947
por: Tikhomirova, Alexandra, et al.
Publicado: (2022)

Unraveling the Complexity of Supramolecular Copolymerization Dictated by Triazine–Benzene Interactions
por: Su, Hao, et al.
Publicado: (2021)

Funneled potential and flux landscapes dictate the stabilities of both the states and the flow: Fission yeast cell cycle
por: Luo, Xiaosheng, et al.
Publicado: (2017)

AdcAII of Streptococcus pneumoniae Affects Pneumococcal Invasiveness
por: Brown, Lindsey R., et al.
Publicado: (2016)

Streptococcus pneumoniae induces pyroptosis through the regulation of autophagy in murine microglia
por: Kim, Ji-Yun, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_m1onl18rqrt36du75pm7ph6d1j