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Role of 11β-hydroxysteroid dehydrogenase type 1 in the development of atopic dermatitis

Glucocorticoids (GCs) are potent anti-inflammatory drugs, the secretion of which is mediated and controlled by the hypothalamic–pituitary–adrenal axis. However, they are also secreted de novo by peripheral tissues for local use. Several tissues express 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1),...

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Detalles Bibliográficos
Autores principales: Lee, Noo Ri, Kim, Beom Jun, Lee, Chung Hyeok, Lee, Young Bin, Lee, Solam, Hwang, Hyun Jee, Kim, Eunjung, Kim, Sung Hee, Lee, Min-Geol, Lee, Sang Eun, Lavery, Gareth G., Choi, Eung Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678864/
https://www.ncbi.nlm.nih.gov/pubmed/33214595
http://dx.doi.org/10.1038/s41598-020-77281-x